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catenin delta 2

Summary

Gene Symbol

CTNND2

Organism

Homo sapiens (human)

External Links

NCBI Gene

1501

PubChem

1501

Alliance of Genome Resources

HGNC:2516

Annotation

Keyword

Alternative splicing
Autism
Cell adhesion
Cell junction
Cell projection
Coiled coil
Developmental protein
Disease variant
Glycoprotein
Methylation
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Transcription regulation
Wnt signaling pathway

Proteins

Displaying **all 4** entries
UniProt	Protein Name
B4DJU1
Q9UQB3	Delta-catenin GT24 Neural plakophilin-related ARM-repeat protein Neurojungin
B4DRK2
E7EPC8

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
cell adhesion	TAS	9223106
signal transduction	TAS	9223106
Wnt signaling pathway	IEA
synapse organization	IMP	25807484
regulation of canonical Wnt signaling pathway	IMP	25807484

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cell-cell adhesion

signal transduction

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

dendritic spine morphogenesis

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

dendritic spine morphogenesis

neuron projection organization [inference]

dendritic spine organization [inference]

dendritic spine morphogenesis

cell junction organization [inference]

synapse organization

postsynapse organization [inference]

dendritic spine organization [inference]

dendritic spine morphogenesis

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

dendritic spine morphogenesis

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of Wnt signaling pathway [inference]

regulation of canonical Wnt signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of Wnt signaling pathway [inference]

regulation of canonical Wnt signaling pathway

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of Wnt signaling pathway [inference]

regulation of canonical Wnt signaling pathway

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GO Term	Evidence Code	PMID
nucleus	IBA
cytoplasm	IBA
plasma membrane	IBA
adherens junction	IBA
postsynaptic density	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

adherens junction

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

perikaryon

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

postsynaptic specialization [inference]

postsynaptic density

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	19706605 19706687 22022388 24550280 25009281 30126976
beta-catenin binding	IPI	25807484
cadherin binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

beta-catenin binding

cell adhesion molecule binding [inference]

cadherin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Catenin delta-2

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
cadherin binding
cell-cell junction assembly

Displaying **all 4** entries
InterPro
Armadillo-like helical
Armadillo-type fold
Armadillo
Plakophilin/Delta catenin

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:1470	major depressive disorder	Alliance of Genome Resources
DOID:2030	anxiety disorder	Alliance of Genome Resources
DOID:5419	schizophrenia	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of 51 in total

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Species	Gene ID	Orthologous MAtrix
Nomascus leucogenys	100581918	NOMLE31955
Otolemur garnettii	100965189	OTOGA12256
Papio anubis	101016786	PAPAN32330
Saimiri boliviensis boliviensis	101037727	SAIBB20722
Felis catus	101092165	FELCA01783
Gorilla gorilla gorilla	101132039	GORGO13419
Octodon degus	101584713	OCTDE02788
Jaculus jaculus	101609923	JACJA03790
Melopsittacus undulatus	101870564	MELUD00776
Chrysemys picta bellii	101938494	CHRPI14887

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements