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MIRAGE
major depressive disorder
Summary
- Synonym
-
- clinical depression
- major depression
- recurrent major depression
- single major depressive episode
- unipolar depression
- Definition
- A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.
- Super Class
- depressive disorder
External Links
- Disease Ontology
- DOID:1470
- Mondo Disease Ontology
- UMLS
- NCI Thesaurus
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 1129 | CHRM2 | cholinergic receptor muscarinic 2 | |
| 1501 | CTNND2 | catenin delta 2 | |
| 2908 | NR3C1 | nuclear receptor subfamily 3 group C member 1 | |
| 3303 | HSPA1A | heat shock protein family A (Hsp70) member 1A | |
| 3305 | HSPA1L | heat shock protein family A (Hsp70) member 1 like | |
| 3351 | HTR1B | 5-hydroxytryptamine receptor 1B | |
| 3356 | HTR2A | 5-hydroxytryptamine receptor 2A | |
| 3569 | IL6 | interleukin 6 | |
| 3586 | IL10 | interleukin 10 | |
| 4157 | MC1R | melanocortin 1 receptor |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| O15409 | Forkhead box protein P2 | |
| P04150 | Glucocorticoid receptor | |
| P05231 | Interleukin-6 | |
| P08172 | Muscarinic acetylcholine receptor M2 | |
| P0DMV8 | Heat shock 70 kDa protein 1A | |
| P22301 | Interleukin-10 | |
| P28222 | 5-hydroxytryptamine receptor 1B | |
| P28223 | 5-hydroxytryptamine receptor 2A | |
| P31645 | Sodium-dependent serotonin transporter | |
| P34931 | Heat shock 70 kDa protein 1-like |
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q68ED7 | CREB-regulated transcription coactivator 1 | |
| Q8VHH7 | Adenylate cyclase type 3 |
| UniProt ID | Protein Name | Source |
|---|---|---|
| P08909 | 5-hydroxytryptamine receptor 2C |
