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MIRAGE
5-hydroxytryptamine receptor 1B

Summary
UniProt ID
P28222
Gene Symbol
  • HTR1B
  • HTR1DB
Gene ID
3351
Organism
Homo sapiens (human)
GlyGen
P28222
PubChem
P28222
The Human Metabolome Database
HMDBP02400
Re-Glyco
P28222
Annotation
Keyword
  • 3D-structure
  • Behavior
  • Cell membrane
  • Disulfide bond
  • G-protein coupled receptor
  • Glycoprotein
  • Palmitate
  • Phosphoprotein
  • Reference proteome
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 7 entries
GO Term
plasma membrane
dendrite
endoplasmic reticulum
presynaptic membrane
calyx of Held
G protein-coupled serotonin receptor complex
serotonergic synapse
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTS
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 3 entries
Position Description PubMed ID GlyTouCan ID Source
24 N-linked (GlcNAc...) asparagine
32 N-linked (GlcNAc...) asparagine
265
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
G alpha (i) signalling events Homo sapiens
Serotonin receptors Homo sapiens
Disease
Displaying all 9 entries
DO ID Disease Name Source
DOID:0050741 alcohol dependence
DOID:0050742 nicotine dependence
DOID:10939 antisocial personality disorder
DOID:1094 attention deficit hyperactivity disorder
DOID:12995 conduct disorder
DOID:14320 generalized anxiety disorder
DOID:1470 major depressive disorder
DOID:1574 alcohol use disorder
DOID:302 substance abuse
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025