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high mobility group box 1
Summary
- Gene Symbol
-
- Hmgb1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- ADP-ribosylation
- Acetylation
- Adaptive immunity
- Autophagy
- Cell membrane
- Chemotaxis
- Chromosome
- Cytoplasm
- DNA recombination
- DNA repair
- DNA-binding
- Direct protein sequencing
- Disulfide bond
- Endosome
- Heparin-binding
- Inflammatory response
- Innate immunity
- Isopeptide bond
- Nucleus
- Oxidation
- Phosphoprotein
- Reference proteome
- Repeat
- Secreted
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of restriction endodeoxyribonuclease activity | ||
| positive regulation of toll-like receptor 9 signaling pathway |
|
|
| positive regulation of mitotic cell cycle | ||
| positive regulation of DNA binding | ||
| immune system process |
GO Hierarchy
- regulation of tolerance induction
biological process
immune system process
metabolic process [inference]
cellular process [inference]
multicellular organismal process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
negative regulation of immune system process [inference]
positive regulation of immune system process [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of immune response [inference]
regulation of hemopoiesis [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
regulation of DNA-templated transcription [inference]
positive regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
regulation of RNA biosynthetic process [inference]
negative regulation of cellular biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
negative regulation of metabolic process [inference]
negative regulation of biosynthetic process [inference]
negative regulation of macromolecule metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
regulation of DNA-templated transcription [inference]
positive regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
regulation of RNA biosynthetic process [inference]
negative regulation of cellular biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of nitrogen compound metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
regulation of DNA-templated transcription [inference]
positive regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
regulation of RNA biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
negative regulation of macromolecule metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of signaling [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of response to stimulus [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of biological process [inference]
negative regulation of immune system process [inference]
negative regulation of metabolic process [inference]
negative regulation of biosynthetic process [inference]
negative regulation of macromolecule metabolic process [inference]
negative regulation of cellular metabolic process [inference]
negative regulation of cellular process [inference]
negative regulation of multicellular organismal process [inference]
regulation of response to stimulus [inference]
regulation of response to biotic stimulus [inference]
regulation of signal transduction [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
regulation of immune response [inference]
regulation of response to stress [inference]
regulation of developmental process [inference]
regulation of cell differentiation [inference]
regulation of multicellular organismal development [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cell adhesion [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
regulation of DNA-templated transcription [inference]
positive regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
regulation of RNA biosynthetic process [inference]
negative regulation of cellular biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of cell population proliferation [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
negative regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
negative regulation of cell activation [inference]
regulation of cellular component organization [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
regulation of epithelial cell migration [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
negative regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of multicellular organismal process [inference]
regulation of multicellular organismal development [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| RNA polymerase II-specific DNA-binding transcription factor binding | ||
| DNA binding | ||
| cytokine activity | ||
| DNA binding, bending | ||
| double-stranded DNA binding |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10908 | hydrocephalus | |
| DOID:11446 | sciatic neuropathy | |
| DOID:13378 | Kawasaki disease | |
| DOID:13603 | obstructive jaundice | |
| DOID:1936 | atherosclerosis | |
| DOID:234 | colon adenocarcinoma | |
| DOID:3070 | high grade glioma | |
| DOID:332 | amyotrophic lateral sclerosis | |
| DOID:3454 | brain infarction | |
| DOID:3525 | middle cerebral artery infarction |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 175890 | WB:WBGene00001972 | ||
| 117294 | FB:FBgn0278608 | ||
| 778643 | CIOIN04472 | ||
| 116942951 | PETMA06498 | ||
| 103178357 | CALMI01850 | ||
| 103180230 | CALMI19879 | ||
| 102366474 | LATCH03573 | ||
| 321622 | ZFIN:ZDB-GENE-030131-341 | DANRE47945 | |
| 795095 | ZFIN:ZDB-GENE-030131-8480 | DANRE08185 | |
| 110438871 | DANRE47945 |
