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cilia and flagella associated protein 58
Summary
- Gene Symbol
-
- CFAP58
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cilium biogenesis/degradation
- Coiled coil
- Cytoskeleton
- Disease variant
- Flagellum
- Proteomics identification
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| Q5T655 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| Notch signaling pathway | ||
| sperm axoneme assembly | ||
| flagellated sperm motility | ||
| cilium assembly | ||
| protein localization to motile cilium |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular space | ||
| cytoplasm | ||
| centrosome | ||
| cytoskeleton | ||
| sperm flagellum |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- coiled-coil domain-containing protein
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| Cilia- and flagella-associated protein 58, central coiled coil |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0112271 | spermatogenic failure 49 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 159686 | Xenbase:XB-GENE-5719803 | ||
| 381229 | MOUSE26681 | ||
| 450722 | PANTR01512 | ||
| 477815 | CANLF11460 | ||
| 561732 | DANRE17413 | ||
| 716289 | MACMU46770 | ||
| 100028284 | MONDO06364 | ||
| 100069546 | HORSE16750 | ||
| 100081713 | ORNAN07933 | ||
| 100152602 | PIGXX08471 |
