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MIRAGE
inositol 1,4,5-triphosphate receptor 3
Summary
- Gene Symbol
-
- Itpr3
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Calcium channel
- Cytoplasmic vesicle
- Disulfide bond
- Endoplasmic reticulum
- Ligand-gated ion channel
- Metal-binding
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Transmembrane helix
- Zinc
- Proteins
| UniProt | Protein Name |
|---|---|
| P70227 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to calcium ion | ||
| calcium ion homeostasis | ||
| platelet activation | ||
| memory | ||
| calcium ion transmembrane transport |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| receptor complex |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein-containing complex binding | ||
| inositol 1,3,4,5 tetrakisphosphate binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- inositol 1,4,5-trisphosphate receptor type 3
- Functional Category
-
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060041 | autism spectrum disorder | |
| DOID:10591 | pre-eclampsia | |
| DOID:10595 | Charcot-Marie-Tooth disease | |
| DOID:11714 | gestational diabetes | |
| DOID:1441 | autosomal dominant cerebellar ataxia | |
| DOID:9744 | type 1 diabetes mellitus | |
| DOID:9970 | obesity |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 3710 | HGNC:6182 | HUMAN84359 | ||
| 25679 | 10116_1:0051fb | RGD:2934 | RATNO22044 | |
| 40664 | FB:FBgn0010051 | |||
| 177546 | WB:WBGene00002173 | |||
| 281879 | BOVIN18302 | |||
| 462618 | PANTR37920 | |||
| 481746 | CANLF02641 | |||
| 718040 | MACMU34185 | |||
| 794666 | ZFIN:ZDB-GENE-070605-1 | DANRE43485 | ||
| 100025596 | MONDO13468 |
