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UDP-glucose 4-epimerase

Summary

Gene Symbol

gale-1

Organism

Caenorhabditis elegans

External Links

NCBI Gene

173171

PubChem

173171

Alliance of Genome Resources

WB:WBGene00008132

Annotation

Keyword

Alternative splicing
Galactose metabolism
Isomerase
NAD
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q564Q1	Galactowaldenase UDP-N-acetylgalactosamine 4-epimerase UDP-N-acetylglucosamine 4-epimerase UDP-galactose 4-epimerase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
positive regulation of vulval development	IMP	25298520
IRE1-mediated unfolded protein response	HEP	16184190
carbohydrate metabolic process	IEA
negative regulation of endoplasmic reticulum unfolded protein response	IMP	25298520
nematode larval development	IMP	25298520

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

small molecule catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

primary metabolic process [inference]

carbohydrate metabolic process

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

galactose metabolic process

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

small molecule metabolic process

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

galactose metabolic process

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

small molecule catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

organic substance metabolic process [inference]

carbohydrate metabolic process

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

galactose metabolic process

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

cellular process [inference]

signal transduction [inference]

endoplasmic reticulum unfolded protein response [inference]

IRE1-mediated unfolded protein response

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response [inference]

IRE1-mediated unfolded protein response

reproductive process [inference]

developmental process involved in reproduction [inference]

gonad morphogenesis

multicellular organismal process [inference]

multicellular organism development [inference]

larval development [inference]

nematode larval development

embryo development [inference]

embryo development ending in birth or egg hatching

post-embryonic development [inference]

larval development [inference]

nematode larval development

developmental process [inference]

developmental process involved in reproduction [inference]

gonad morphogenesis

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

gonad morphogenesis

anatomical structure development [inference]

multicellular organism development [inference]

larval development [inference]

nematode larval development

embryo development [inference]

embryo development ending in birth or egg hatching

cuticle development

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response [inference]

IRE1-mediated unfolded protein response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response [inference]

IRE1-mediated unfolded protein response

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of distal tip cell migration

positive regulation of biological process [inference]

positive regulation of developmental process [inference]

positive regulation of vulval development

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response

regulation of developmental process [inference]

regulation of vulval development [inference]

positive regulation of vulval development

positive regulation of developmental process [inference]

positive regulation of vulval development

regulation of cellular process [inference]

signal transduction [inference]

endoplasmic reticulum unfolded protein response [inference]

IRE1-mediated unfolded protein response

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of endoplasmic reticulum unfolded protein response

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

negative regulation of endoplasmic reticulum unfolded protein response

negative regulation of response to endoplasmic reticulum stress [inference]

negative regulation of endoplasmic reticulum unfolded protein response

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of distal tip cell migration

Displaying 1 entry
GO Term	Evidence Code	PMID
cytosol	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying **all 3** entries
GO Term	Evidence Code	PMID
UDP-glucose 4-epimerase activity	IBA IEA IMP	25298520
UDP-N-acetylglucosamine 4-epimerase activity	IEA IMP	25298520
isomerase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

isomerase activity

racemase and epimerase activity [inference]

racemase and epimerase activity, acting on carbohydrates and derivatives [inference]

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0111458	galactose epimerase deficiency	Alliance of Genome Resources
DOID:1588	thrombocytopenia	Alliance of Genome Resources
DOID:9870	galactosemia	Alliance of Genome Resources

Ortholog

Displaying **all 7** entries
Species	Gene ID	Alliance of Genome Resources
Drosophila melanogaster	38076	FB:FBgn0035147
Danio rerio	678540	ZFIN:ZDB-GENE-060421-6479
Xenopus tropicalis	448443	Xenbase:XB-GENE-965029
Homo sapiens	2582	HGNC:4116
Mus musculus	74246	MGI:1921496
Rattus norvegicus	114860	RGD:621493
Saccharomyces cerevisiae S288C	852307	SGD:S000000223