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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

Torsin-like protein

Summary

Gene Symbol

ooc-5

Organism

Caenorhabditis elegans

External Links

NCBI Gene

174433

PubChem

174433

Alliance of Genome Resources

WB:WBGene00003870

Annotation

Keyword

ATP-binding
Alternative splicing
Endoplasmic reticulum
Glycoprotein
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q95NU5	Abnormal oocyte formation protein 5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
chaperone cofactor-dependent protein refolding	IEA
cellular response to misfolded protein	IDA	12554684
cellular response to misfolded protein	IBA

GO Hierarchy

biological process

cellular process [inference]

protein folding [inference]

'de novo' protein folding [inference]

'de novo' post-translational protein folding [inference]

chaperone cofactor-dependent protein refolding

chaperone-mediated protein folding [inference]

chaperone cofactor-dependent protein refolding

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to topologically incorrect protein [inference]

cellular response to misfolded protein

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to topologically incorrect protein [inference]

cellular response to misfolded protein

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to topologically incorrect protein [inference]

cellular response to misfolded protein

response to topologically incorrect protein [inference]

cellular response to topologically incorrect protein [inference]

cellular response to misfolded protein

response to misfolded protein [inference]

cellular response to misfolded protein

response to chemical [inference]

response to organic substance [inference]

response to topologically incorrect protein [inference]

cellular response to topologically incorrect protein [inference]

cellular response to misfolded protein

response to misfolded protein [inference]

cellular response to misfolded protein

cellular response to organic substance [inference]

cellular response to topologically incorrect protein [inference]

cellular response to misfolded protein

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to topologically incorrect protein [inference]

cellular response to misfolded protein

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to topologically incorrect protein [inference]

cellular response to misfolded protein

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to topologically incorrect protein [inference]

cellular response to misfolded protein

Displaying entries **1 - 5** of 10 in total

1

2

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GO Term	Evidence Code	PMID
spindle pole	IDA	11714689
cytoplasm	IEA
endoplasmic reticulum	IDA	11714689
endoplasmic reticulum	IEA
endoplasmic reticulum lumen	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

endoplasmic reticulum

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle

endoplasmic reticulum

intracellular non-membrane-bounded organelle [inference]

perinuclear region of cytoplasm

supramolecular complex [inference]

aster

Displaying **all 2** entries
GO Term	Evidence Code	PMID
ATP binding	IEA
ATP hydrolysis activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

torsin A

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
ATP binding

Displaying **all 3** entries
InterPro
P-loop containing nucleoside triphosphate hydrolase
Torsin-1A, C-terminal domain
Torsin

Alliance of Genome Resources

Expression

Displaying **all 6** entries
Location	References
spindle	PMID:11714689
aster	PMID:11714689
plasma membrane	PMID:11714689
endoplasmic reticulum	PMID:11714689
perinuclear region of cytoplasm	PMID:11714689
spindle pole	PMID:11714689

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060730	torsion dystonia 1	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 14 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	1861	Xenbase:XB-GENE-943837
Xenopus tropicalis	27348	Xenbase:XB-GENE-986914
Xenopus tropicalis	27433	Xenbase:XB-GENE-5806617
Xenopus tropicalis	30931	Xenbase:XB-GENE-943837
Xenopus tropicalis	30933	Xenbase:XB-GENE-5806617
Xenopus tropicalis	30934	Xenbase:XB-GENE-986914
Danio rerio	30935	ZFIN:ZDB-GENE-081104-165
Xenopus tropicalis	31399	Xenbase:XB-GENE-5806617
Danio rerio	64222	ZFIN:ZDB-GENE-081104-165
Xenopus tropicalis	174433	Xenbase:XB-GENE-5806617

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Last updated: April 7, 2025