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advanced glycosylation end-product specific receptor
Summary
- Gene Symbol
-
- AGER
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Inflammatory response
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane helix
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| B4DNX3 |
|
| Q15109 |
|
| A0A1U9X785 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to wounding | ||
| positive regulation of monocyte extravasation | ||
| microglial cell activation | ||
| regulation of non-canonical NF-kappaB signal transduction | ||
| positive regulation of tumor necrosis factor production |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of protein metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of response to stimulus [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
positive regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
positive regulation of cell communication [inference]
regulation of cell adhesion [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of cell population proliferation [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of cell activation [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
regulation of tissue remodeling [inference]
regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell junction | ||
| postsynapse | ||
| apical plasma membrane | ||
| plasma membrane | ||
| extracellular region |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| advanced glycation end-product receptor activity | ||
| scavenger receptor activity | ||
| protein-containing complex binding | ||
| identical protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Uncharacterized protein
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| T cell receptor signaling pathway |
| signaling receptor binding |
| InterPro |
|---|
| Immunoglobulin V-set domain |
| Immunoglobulin subtype |
| Immunoglobulin-like domain superfamily |
| Immunoglobulin-like domain |
| Immunoglobulin-like fold |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050697 | chorioamnionitis | |
| DOID:0050850 | diabetic encephalopathy | |
| DOID:0050855 | renal fibrosis | |
| DOID:0060224 | atrial fibrillation | |
| DOID:0080162 | lupus nephritis | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:0080832 | mild cognitive impairment | |
| DOID:10283 | prostate cancer | |
| DOID:10646 | schizotypal personality disorder |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 11596 | MGI:893592 | MOUSE20236 | ||
| 81722 | RGD:69258 | RATNO22232 | ||
| 280986 | BOVIN18719 | |||
| 396591 | PIGXX31232 | |||
| 403168 | CANLF02590 | |||
| 462584 | 9598_0:001bf5 | PANTR37811 | ||
| 717296 | MACMU34838 | |||
| 100024116 | MONDO13031 | |||
| 100343142 | RABIT02230 | |||
| 100414002 | CALJA32278 |
