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Metalloprotease mig-17

Summary

Gene Symbol

mig-17

Organism

Caenorhabditis elegans

External Links

NCBI Gene

179575

PubChem

179575

Alliance of Genome Resources

WB:WBGene00003248

Annotation

Keyword

Basement membrane
Cleavage on pair of basic residues
Developmental protein
Disulfide bond
Glycoprotein
Metal-binding
Metalloprotease
Reference proteome
Repeat
Signal
Zinc
Zymogen

Proteins

Displaying 1 entry
UniProt	Protein Name
Q20930	Abnormal cell migration protein 17

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
proteolysis	IEA
protein localization	IMP	19104038
protein autoprocessing	IDA	18637819
protein autoprocessing	IMP	17491590
regulation of cell migration	IMP	10864868 14688791

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing [inference]

protein maturation [inference]

protein processing [inference]

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing [inference]

protein maturation [inference]

protein processing [inference]

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing [inference]

protein maturation [inference]

protein processing [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing [inference]

protein maturation [inference]

protein processing [inference]

cellular process [inference]

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization

reproductive process [inference]

developmental process involved in reproduction [inference]

gonad morphogenesis

developmental process [inference]

developmental process involved in reproduction [inference]

gonad morphogenesis

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

gonad morphogenesis

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration

regulation of distal tip cell migration

regulation of cellular process [inference]

regulation of cell motility [inference]

regulation of cell migration

regulation of distal tip cell migration

Displaying **all 5** entries
GO Term	Evidence Code	PMID
extracellular region	IEA
basement membrane	IDA	10864868 16354716 18637819 25298520
basement membrane	IMP	17491590
basement membrane	IEA
extracellular space	IDA	14688791 16354716

GO Hierarchy

cellular component

cellular anatomical entity [inference]

external encapsulating structure [inference]

extracellular matrix [inference]

collagen-containing extracellular matrix [inference]

basement membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
metalloendopeptidase activity	ISS	10864868
metalloendopeptidase activity	IEA
metallopeptidase activity	IDA	18637819
metallopeptidase activity	IMP	17491590
metallopeptidase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity

metalloendopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity

metalloendopeptidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

thrombospondin

Functional Category

E: Amino acid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
extracellular matrix organization
metal ion binding
metalloendopeptidase activity
metallopeptidase activity
proteolysis

Displaying **all 5** entries
InterPro
ADAMTS, cysteine-rich domain 2
Metallopeptidase, catalytic domain superfamily
Peptidase M12B, ADAM/reprolysin
Thrombospondin type-1 (TSP1) repeat superfamily
Thrombospondin type-1 (TSP1) repeat

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
basement membrane	PMID:10864868 PMID:24318535
cell surface	PMID:17491590
cytoplasm	PMID:10864868

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	170692	Xenbase:XB-GENE-986196
Xenopus tropicalis	179575	Xenbase:XB-GENE-986196
Xenopus tropicalis	181412	Xenbase:XB-GENE-986196
Xenopus tropicalis	208936	Xenbase:XB-GENE-986196

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements