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Glutamate-gated chloride channel alpha

Summary

Gene Symbol

glc-1

Organism

Caenorhabditis elegans

External Links

NCBI Gene

180086

PubChem

180086

Alliance of Genome Resources

WB:WBGene00001591

Annotation

Keyword

3D-structure
Cell membrane
Chloride
Disulfide bond
Glycoprotein
Ion channel
Postsynaptic cell membrane
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
G5EBR3	Avermectin-sensitive glutamate-gated chloride channel GluCl alpha GluCl alpha

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
monoatomic ion transport	IEA
ion transport	IEA
locomotion involved in locomotory behavior	IMP	16527366
locomotion involved in locomotory behavior	IGI	16527366
ion transmembrane transport	IEA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization

locomotion [inference]

locomotion involved in locomotory behavior

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport

monoatomic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

monoatomic ion transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

biological regulation [inference]

regulation of biological quality [inference]

regulation of membrane potential [inference]

regulation of postsynaptic membrane potential [inference]

excitatory postsynaptic potential

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
plasma membrane	IDA	7935817
plasma membrane	IEA
membrane	IEA
neuron projection
synapse	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

transmembrane transporter complex

transporter complex [inference]

transmembrane transporter complex

cellular anatomical entity [inference]

membrane

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic membrane

cell junction [inference]

synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

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GO Term	Evidence Code	PMID
transmembrane signaling receptor activity	IEA
ion channel activity	IEA
monoatomic ion channel activity	IEA
extracellular ligand-gated monoatomic ion channel activity	IEA
excitatory extracellular ligand-gated monoatomic ion channel activity	IBA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity

monoatomic anion channel activity [inference]

chloride channel activity

extracellularly glutamate-gated chloride channel activity

ligand-gated monoatomic anion channel activity [inference]

extracellularly glutamate-gated chloride channel activity

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity

excitatory extracellular ligand-gated monoatomic ion channel activity

extracellularly glutamate-gated ion channel activity [inference]

extracellularly glutamate-gated chloride channel activity

ligand-gated monoatomic anion channel activity [inference]

extracellularly glutamate-gated chloride channel activity

monoatomic anion transmembrane transporter activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity

extracellularly glutamate-gated chloride channel activity

ligand-gated monoatomic anion channel activity [inference]

extracellularly glutamate-gated chloride channel activity

chloride transmembrane transporter activity [inference]

chloride channel activity

extracellularly glutamate-gated chloride channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic anion transmembrane transporter activity [inference]

chloride transmembrane transporter activity [inference]

chloride channel activity

extracellularly glutamate-gated chloride channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity

monoatomic anion channel activity [inference]

chloride channel activity

extracellularly glutamate-gated chloride channel activity

ligand-gated monoatomic anion channel activity [inference]

extracellularly glutamate-gated chloride channel activity

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity

excitatory extracellular ligand-gated monoatomic ion channel activity

extracellularly glutamate-gated ion channel activity [inference]

extracellularly glutamate-gated chloride channel activity

ligand-gated monoatomic anion channel activity [inference]

extracellularly glutamate-gated chloride channel activity

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity

excitatory extracellular ligand-gated monoatomic ion channel activity

extracellularly glutamate-gated ion channel activity [inference]

extracellularly glutamate-gated chloride channel activity

ligand-gated monoatomic anion channel activity [inference]

extracellularly glutamate-gated chloride channel activity

salt transmembrane transporter activity [inference]

chloride transmembrane transporter activity [inference]

chloride channel activity

extracellularly glutamate-gated chloride channel activity

binding [inference]

protein binding [inference]

identical protein binding

amide binding [inference]

glutamate binding

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

amino acid binding [inference]

glutamate binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

amino acid binding [inference]

glutamate binding

molecular transducer activity [inference]

signaling receptor activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

gamma-aminobutyric acid receptor

Functional Category

E: Amino acid transport and metabolism
T: Signal transduction mechanisms
X: Mobilome: prophages, transposons

Displaying **all 7** entries
Gene Ontology
chloride channel activity
chloride transmembrane transport
excitatory extracellular ligand-gated monoatomic ion channel activity
extracellular ligand-gated monoatomic ion channel activity
monoatomic ion channel activity
monoatomic ion transport
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

Displaying **all 8** entries
InterPro
Gamma-aminobutyric acid A receptor/Glycine receptor alpha
Neuronal acetylcholine receptor
Neurotransmitter-gated ion-channel ligand-binding domain superfamily
Neurotransmitter-gated ion-channel ligand-binding domain
Neurotransmitter-gated ion-channel transmembrane domain superfamily
Neurotransmitter-gated ion-channel transmembrane domain
Neurotransmitter-gated ion-channel, conserved site
Neurotransmitter-gated ion-channel

Ortholog

Displaying entries **1 - 10** of 16 in total

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Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	2741	Xenbase:XB-GENE-6035798
Xenopus tropicalis	2742	Xenbase:XB-GENE-958032
Danio rerio	2743	ZFIN:ZDB-GENE-040801-106
Xenopus tropicalis	8001	Xenbase:XB-GENE-1011160
Xenopus tropicalis	14654	Xenbase:XB-GENE-6035798
Danio rerio	14657	ZFIN:ZDB-GENE-020402-2
Danio rerio	14658	ZFIN:ZDB-GENE-040801-106
Xenopus tropicalis	24397	Xenbase:XB-GENE-958032
Danio rerio	25456	ZFIN:ZDB-GENE-040801-106
Xenopus tropicalis	25674	Xenbase:XB-GENE-6035798