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GDP-fucose protein O-fucosyltransferase 1

Summary

Gene Symbol

pfut-1

Organism

Caenorhabditis elegans

External Links

NCBI Gene

180607

KEGG Gene ID

cel:CELE_C15C7.7

PubChem

180607

Alliance of Genome Resources

WB:WBGene00015793

Annotation

Keyword

3D-structure
Disulfide bond
Endoplasmic reticulum
Fucose metabolism
Glycoprotein
Glycosyltransferase
Manganese
Notch signaling pathway
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q18014	Peptide-O-fucosyltransferase 1 Protein O-fucosyltransferase 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

1

2

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GO Term	Evidence Code	PMID
protein O-linked glycosylation	ISS	11524432
carbohydrate metabolic process	IEA
Notch signaling pathway	IEA
organic substance metabolic process	IEA
fucose metabolic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation

protein O-linked fucosylation

primary metabolic process

carbohydrate metabolic process

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation

protein O-linked fucosylation

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process

glycosylation [inference]

fucosylation [inference]

protein O-linked fucosylation

macromolecule glycosylation [inference]

protein glycosylation

protein O-linked glycosylation

protein O-linked fucosylation

organic substance metabolic process

carbohydrate metabolic process

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation

protein O-linked fucosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation

protein O-linked fucosylation

macromolecule glycosylation [inference]

protein glycosylation

protein O-linked glycosylation

protein O-linked fucosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation

protein O-linked fucosylation

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum	IEA ISS	21966509

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 4** entries
GO Term	Evidence Code	PMID
glycosyltransferase activity	IEA
peptide-O-fucosyltransferase activity	IDA IEA	21966509
transferase activity	IEA
fucosyltransferase activity	ISS	11524432

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity

glycosyltransferase activity

hexosyltransferase activity [inference]

fucosyltransferase activity

peptide-O-fucosyltransferase activity

catalytic activity, acting on a protein [inference]

peptide-O-fucosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K03691

Name

peptide-O-fucosyltransferase [EC:2.4.1.221]

References

11524432

Rhea

RHEA:63644

GDP-β-L-fucose

H⁺ + GDP

Enzyme

2.4.1.221

PMID

RHEA:70539

GDP-β-L-fucose

H⁺ + GDP

Enzyme

2.4.1.221

PMID

RHEA:70491

GDP-β-L-fucose

H⁺ + GDP

Enzyme

2.4.1.221

PMID

RHEA:70535

GDP-β-L-fucose

H⁺ + GDP

Enzyme

2.4.1.221

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060256	Dowling-Degos disease	Alliance of Genome Resources

Ortholog

Displaying **all 6** entries
Species	Gene ID	Alliance of Genome Resources
Drosophila melanogaster	36564	FB:FBgn0033901
Danio rerio	403029	ZFIN:ZDB-GENE-040303-2
Xenopus tropicalis	496411	Xenbase:XB-GENE-979243
Homo sapiens	23509	HGNC:14988
Mus musculus	140484	MGI:2153207
Rattus norvegicus	311551	RGD:1303001

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements