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Acetylcholinesterase 1
Summary
- Gene Symbol
-
- ace-1
- Organism
- Caenorhabditis elegans
Annotation
- Keyword
-
- Cell membrane
- Disulfide bond
- Glycoprotein
- Neurotransmitter degradation
- Reference proteome
- Secreted
- Serine esterase
- Signal
- Synapse
- Proteins
| UniProt | Protein Name |
|---|---|
| P38433 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| acetylcholine catabolic process in synaptic cleft | ||
| acetylcholine catabolic process | ||
| choline metabolic process | ||
| regulation of locomotion |
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| extracellular region | ||
| synaptic cleft | ||
| extracellular space | ||
| synapse |
| GO Term | Evidence Code | PMID |
|---|---|---|
| carboxylic ester hydrolase activity | ||
| cholinesterase activity | ||
| identical protein binding | ||
| acetylcholinesterase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- hydrolase
- Functional Category
-
- E: Amino acid transport and metabolism
- I: Lipid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| hydrolase activity |
| InterPro |
|---|
| Alpha/Beta hydrolase fold |
| Carboxylesterase, type B |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:655 | inherited metabolic disorder | |
| DOID:8645 | subacute delirium | |
| DOID:9279 | hyperhomocysteinemia | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9470 | bacterial meningitis | |
| DOID:9505 | cannabis abuse | |
| DOID:9744 | type 1 diabetes mellitus | |
| DOID:9974 | drug dependence | |
| DOID:9976 | heroin dependence |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 36375646 | 34506_0:000195 | |||
| 66060132 | 6279_0:0027bc | |||
| 100135377 | Xenbase:XB-GENE-5842192 | |||
| 100490673 | Xenbase:XB-GENE-923160 | |||
| 100495889 | Xenbase:XB-GENE-980117 |
