heroin dependence

Summary
Definition
An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.
Super Class
opiate dependence
Disease Ontology
DOID:9976
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
Related Genes
Displaying entries 1 - 10 of 35 in total
Gene ID Gene Symbol Description Source
18 ABAT 4-aminobutyrate aminotransferase
43 ACHE acetylcholinesterase (Yt blood group)
148 ADRA1A adrenoceptor alpha 1A
217 ALDH2 aldehyde dehydrogenase 2 family member
355 FAS Fas cell surface death receptor
590 BCHE butyrylcholinesterase
627 BDNF brain derived neurotrophic factor
1129 CHRM2 cholinergic receptor muscarinic 2
1312 COMT catechol-O-methyltransferase
1385 CREB1 cAMP responsive element binding protein 1
Displaying entries 1 - 10 of 34 in total
Gene ID Gene Symbol Description Source
11423 Ache acetylcholinesterase
11549 Adra1a adrenergic receptor, alpha 1a
11669 Aldh2 aldehyde dehydrogenase 2, mitochondrial
12038 Bche butyrylcholinesterase
12064 Bdnf brain derived neurotrophic factor
12846 Comt catechol-O-methyltransferase
13095 Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29
13162 Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
13488 Drd1 dopamine receptor D1
13489 Drd2 dopamine receptor D2
Displaying entries 1 - 10 of 25 in total
Gene ID Gene Symbol Description Source
24225 Bdnf brain-derived neurotrophic factor
24267 Comt catechol-O-methyltransferase
24318 Drd2 dopamine receptor D2
24409 Grin2a glutamate ionotropic receptor NMDA type subunit 2A
24415 Grm2 glutamate metabotropic receptor 2
24613 Oprd1 opioid receptor, delta 1
24898 Slc6a3 solute carrier family 6 member 3
24922 Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3
25085 Th tyrosine hydroxylase
25453 Gdnf glial cell derived neurotrophic factor
Displaying entries 1 - 10 of 11 in total
Gene ID Gene Symbol Description Source
32554 Lcch3 Ligand-gated chloride channel homolog 3
33007 Dop2R Dopamine 2-like receptor
36428 Mdr49 Multi drug resistance 49
36849 DAT Dopamine transporter
37892 mAChR-A muscarinic Acetylcholine Receptor, A-type
38726 Mdr65 Multi drug resistance 65
38742 GluRIA Glutamate receptor IA
41625 Ace Acetylcholine esterase
41726 Dop1R1 Dopamine 1-like receptor 1
43484 Dop1R2 Dopamine 1-like receptor 2
Displaying all 4 entries
Gene ID Gene Symbol Description Source
58133 ngfb nerve growth factor b (beta polypeptide)
114549 ache acetylcholinesterase (Yt blood group)
561372 comta catechol-O-methyltransferase a
565370 comtb catechol-O-methyltransferase b
Displaying all 4 entries
Gene ID Gene Symbol Description Source Organism
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
779087 gdnf.L glial cell derived neurotrophic factor L homeolog Xenopus laevis (African clawed frog)
100127346 grin2a.L glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog Xenopus laevis (African clawed frog)
108709389 ngf.S nerve growth factor S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 16 in total
Gene ID Gene Symbol Description Source
171905 ace-2 Carboxylic ester hydrolase
175076 ace-3 Carboxylic ester hydrolase
175999 glr-2 Glutamate receptor 2
176204 glr-1 Glutamate receptor 1
176304 dat-1 Sodium-dependent dopamine transporter
176691 gab-1 Gamma-aminobutyric acid receptor subunit beta
178215 pgp-1 Multidrug resistance protein pgp-1
179347 dop-2 Dopamine receptor 2
179962 gar-3 Muscarinic acetylcholine receptor gar-3
180714 dop-1 Dopamine receptor 1
Displaying 1 entry
Gene ID Gene Symbol Description Source
853671 STE6 ATP-binding cassette a-factor transporter STE6

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