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MIRAGE
proenkephalin

Summary
Gene Symbol
  • Penk
Organism
Rattus norvegicus (Norway rat)
NCBI Gene
29237
PubChem
29237
Alliance of Genome Resources
Annotation
Keyword
  • Cleavage on pair of basic residues
  • Cytoplasmic vesicle
  • Direct protein sequencing
  • Disulfide bond
  • Endorphin
  • Neuropeptide
  • Opioid peptide
  • Phosphoprotein
  • Reference proteome
  • Secreted
  • Signal
Proteins
Displaying all 2 entries
UniProt Protein Name
A6JFM8
P04094
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 35 in total
GO Term Evidence Code PMID
osteoblast differentiation
behavioral fear response
response to hypoxia
startle response
aggressive behavior
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
proenkephalin a
Functional Category
  • E: Amino acid transport and metabolism
  • P: Inorganic ion transport and metabolism
  • T: Signal transduction mechanisms
Displaying all 4 entries
Gene Ontology
chemical synaptic transmission
neuropeptide signaling pathway
opioid receptor binding
sensory perception
Displaying all 2 entries
InterPro
Opioid neuropeptide precursor
Proenkephalin A
Alliance of Genome Resources
Expression
Displaying all 7 entries
Location References
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:9976 heroin dependence
Ortholog
Displaying entries 1 - 10 of 67 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
5179 HUMAN93946
18619 Xenbase:XB-GENE-942760 MOUSE42463
29237 Xenbase:XB-GENE-942760
281387 BOVIN05854
464186 PANTR42594
696649 MACMU44726
100022433 MONDO19046
100067723 HORSE43178
100083341 ORNAN24134
100190068 TAEGU18466
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025