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Cyclic AMP-responsive element-binding protein 1

Summary

UniProt ID

P15337

Gene Symbol

Creb1
Creb-1

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P15337
PubChem: P15337
The O-GlcNAc Database: P15337
O-GlcNAcAtlas: P15337

Annotation

Keyword

3D-structure
Activator
Alternative splicing
Biological rhythms
DNA-binding
Differentiation
Direct protein sequencing
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

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GO Term
positive regulation of RNA polymerase II transcription preinitiation complex assembly
regulation of DNA-templated transcription
axonogenesis
positive regulation of DNA-templated transcription
positive regulation of transcription by RNA polymerase II
protein stabilization
response to hypoxia
lactation
memory
circadian rhythm

Displaying **all 9** entries
GO Term
nucleoplasm
RNA polymerase II transcription regulator complex
ATF4-CREB1 transcription factor complex
chromatin
euchromatin
nucleus
mitochondrial matrix
axon
transcription regulator complex

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GO Term
arrestin family protein binding
transcription cis-regulatory region binding
RNA polymerase II transcription regulatory region sequence-specific DNA binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA binding
double-stranded DNA binding
DNA-binding transcription factor activity
enzyme binding

Annotation information from UniProt.

Sequence

MTMDSGADNQQSGDAAVTEAESQQMTVQAQPQIATLAQVSMPAAHATSSAPTVTLVQLPNGQTVQVHGVIQAAQPSVIQSPQVQTVQISTIAESEDSQESVDSVTDSQKRREILSRRPSYRKILNDLSSDAPGVPRIEEEKSEEETSAPAITTVTVPTPIYQTSSGQYIAITQGGAIQLANNGTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	GlyTouCan ID	Source
40	G49108TO	GlyGen The O-GlcNAc Database
245	G49108TO	GlyGen
246	G49108TO	GlyGen
247	G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 7** entries
Pathway Name	Organism
AKT phosphorylates targets in the nucleus	Rattus norvegicus
CREB phosphorylation	Rattus norvegicus
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	Rattus norvegicus
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	Rattus norvegicus
Gastrin-CREB signalling pathway via PKC and MAPK	Rattus norvegicus
NCAM signaling for neurite out-growth	Rattus norvegicus
NGF-stimulated transcription	Rattus norvegicus