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Guidelines
MIRAGE
Cyclic AMP-responsive element-binding protein 1
Summary
- UniProt ID
- P15337
- Gene Symbol
-
- Creb-1
- Creb1
- Gene ID
- 81646
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Activator
- Alternative splicing
- Biological rhythms
- DNA-binding
- Differentiation
- Direct protein sequencing
- Isopeptide bond
- Nucleus
- Phosphoprotein
- Reference proteome
- Transcription regulation
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| response to cocaine |
| lung epithelium development |
| response to hypoxia |
| lactation |
| memory |
| circadian rhythm |
| negative regulation of gene expression |
| cell differentiation |
| osteoclast differentiation |
| mammary gland development |
Sequence
MTMDSGADNQQSGDAAVTEAESQQMTVQAQPQIATLAQVSMPAAHATSSAPTVTLVQLPNGQTVQVHGVIQAAQPSVIQSPQVQTVQISTIAESEDSQESVDSVTDSQKRREILSRRPSYRKILNDLSSDAPGVPRIEEEKSEEETSAPAITTVTVPTPIYQTSSGQYIAITQGGAIQLANNGTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSD
Glycosylation Sites
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| AKT phosphorylates targets in the nucleus | Rattus norvegicus |
| CREB phosphorylation | Rattus norvegicus |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | Rattus norvegicus |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | Rattus norvegicus |
| Gastrin-CREB signalling pathway via PKC and MAPK | Rattus norvegicus |
| NCAM signaling for neurite out-growth | Rattus norvegicus |
| NGF-stimulated transcription | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050741 | alcohol dependence | |
| DOID:0060001 | withdrawal disorder | |
| DOID:0060041 | autism spectrum disorder | |
| DOID:10763 | hypertension | |
| DOID:10914 | amnestic disorder | |
| DOID:10933 | obsessive-compulsive disorder | |
| DOID:11446 | sciatic neuropathy | |
| DOID:1574 | alcohol use disorder | |
| DOID:1596 | depressive disorder | |
| DOID:224 | transient cerebral ischemia |
