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MIRAGE
Cyclic AMP-responsive element-binding protein 1

Summary
UniProt ID
P15337
Gene Symbol
  • Creb-1
  • Creb1
Gene ID
81646
Organism
Rattus norvegicus (Norway rat)
GlyGen
P15337
PubChem
P15337
The O-GlcNAc Database
P15337
O-GlcNAcAtlas
P15337
Re-Glyco
P15337
Annotation
Keyword
  • 3D-structure
  • Activator
  • Alternative splicing
  • Biological rhythms
  • DNA-binding
  • Differentiation
  • Direct protein sequencing
  • Isopeptide bond
  • Nucleus
  • Phosphoprotein
  • Reference proteome
  • Transcription regulation
  • Ubl conjugation
Gene Ontology (GO)
Displaying all 9 entries
GO Term
transcription regulator complex
ATF4-CREB1 transcription factor complex
chromatin
euchromatin
nucleus
mitochondrial matrix
axon
nucleoplasm
RNA polymerase II transcription regulator complex
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MTMDSGADNQQSGDAAVTEAESQQMTVQAQPQIATLAQVSMPAAHATSSAPTVTLVQLPNGQTVQVHGVIQAAQPSVIQSPQVQTVQISTIAESEDSQESVDSVTDSQKRREILSRRPSYRKILNDLSSDAPGVPRIEEEKSEEETSAPAITTVTVPTPIYQTSSGQYIAITQGGAIQLANNGTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSD
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 4 entries
Position Description PubMed ID GlyTouCan ID Source
40
245
246
247
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 7 entries
Pathway Name Organism
AKT phosphorylates targets in the nucleus Rattus norvegicus
CREB phosphorylation Rattus norvegicus
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling Rattus norvegicus
Estrogen-dependent nuclear events downstream of ESR-membrane signaling Rattus norvegicus
Gastrin-CREB signalling pathway via PKC and MAPK Rattus norvegicus
NCAM signaling for neurite out-growth Rattus norvegicus
NGF-stimulated transcription Rattus norvegicus
Disease
Displaying entries 11 - 18 of 18 in total
DO ID Disease Name Source
DOID:2560 morphine dependence
DOID:3525 middle cerebral artery infarction
DOID:6000 congestive heart failure
DOID:809 cocaine abuse
DOID:8725 vascular dementia
DOID:9973 substance dependence
DOID:9975 cocaine dependence
DOID:9976 heroin dependence
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025