GlyCosmos Portal

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GO Term	Evidence Code	PMID
nuclear lamina	IDA	10888872
intracellular anatomical structure	IDA	16489008
PCNA complex	IBA ISO ISS
male germ cell nucleus	IDA	12638230
cyclin-dependent protein kinase holoenzyme complex	IPI	12970760

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-DNA complex [inference]

chromatin

nuclear protein-containing complex [inference]

enzyme activator complex [inference]

DNA polymerase processivity factor complex [inference]

PCNA complex

catalytic complex [inference]

transferase complex [inference]

transferase complex, transferring phosphorus-containing groups [inference]

protein kinase complex [inference]

serine/threonine protein kinase complex [inference]

cyclin-dependent protein kinase holoenzyme complex

cellular anatomical entity [inference]

replication fork

nuclear replication fork

microtubule organizing center [inference]

centrosome

nuclear body

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

germ cell nucleus [inference]

male germ cell nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

germ cell nucleus [inference]

male germ cell nucleus

Displaying entries **11 - 15** of 15 in total

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GO Term	Evidence Code	PMID
receptor tyrosine kinase binding	IEA ISO
MutLalpha complex binding	IEA ISO
nuclear estrogen receptor binding	IEA ISO
dinucleotide insertion or deletion binding	IEA ISO
damaged DNA binding	ISO ISS

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing N-glycosyl compounds [inference]

DNA N-glycosylase activity [inference]

mismatch base pair DNA N-glycosylase activity [inference]

purine-specific mismatch base pair DNA N-glycosylase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

DNA N-glycosylase activity [inference]

mismatch base pair DNA N-glycosylase activity [inference]

purine-specific mismatch base pair DNA N-glycosylase activity

binding [inference]

protein binding

signaling receptor binding [inference]

receptor tyrosine kinase binding

transcription factor binding

DNA-binding transcription factor binding [inference]

RNA polymerase II-specific DNA-binding transcription factor binding [inference]

nuclear receptor binding [inference]

nuclear estrogen receptor binding

enzyme binding

kinase binding [inference]

protein kinase binding [inference]

protein tyrosine kinase binding [inference]

receptor tyrosine kinase binding

identical protein binding

protein-containing complex binding

chromatin binding

mismatch repair complex binding [inference]

MutLalpha complex binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding [inference]

damaged DNA binding

double-stranded DNA binding [inference]

mismatched DNA binding [inference]

DNA insertion or deletion binding [inference]

dinucleotide insertion or deletion binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

DNA polymerase processivity factor activity

molecular function activator activity [inference]

enzyme activator activity [inference]

DNA polymerase processivity factor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

proliferating cell nuclear antigen

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism

Displaying **all 4** entries
Gene Ontology
DNA polymerase processivity factor activity
leading strand elongation
regulation of DNA replication
translesion synthesis

Displaying **all 5** entries
InterPro
DNA clamp superfamily
Proliferating cell nuclear antigen, PCNA, C-terminal
Proliferating cell nuclear antigen, PCNA, N-terminal
Proliferating cell nuclear antigen, PCNA, conserved site
Proliferating cell nuclear antigen, PCNA

Disease

Disease Ontology

Displaying entries **1 - 10** of 17 in total

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DO ID	Disease Name	Source
DOID:0080178	mucositis	Alliance of Genome Resources
DOID:0081385	ataxia-telangiectasia-like disorder-2	Alliance of Genome Resources
DOID:10534	stomach cancer	Alliance of Genome Resources
DOID:11446	sciatic neuropathy	Alliance of Genome Resources
DOID:11476	osteoporosis	Alliance of Genome Resources
DOID:12217	Lewy body dementia	Alliance of Genome Resources
DOID:127	leiomyoma	Alliance of Genome Resources
DOID:13603	obstructive jaundice	Alliance of Genome Resources
DOID:1459	hypothyroidism	Alliance of Genome Resources
DOID:2154	nephroblastoma	Alliance of Genome Resources

Ortholog

Displaying entries **111 - 120** of **133** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Scophthalmus maximus	118314249		SCOMX33162
Onychomys torridus	118582208	38674_0:001780
Balaenoptera musculus	118881856		BALMU20681
Balaenoptera musculus	118898193		BALMU01030
Anas platyrhynchos platyrhynchos	119713445		ANAPP27393
Arvicola amphibius	119814560	1047088_0:00219f
Microtus oregoni	121460225	111838_0:0030f3
Dipodomys spectabilis	122120257	105255_0:0030a5
Panthera leo	122215782		PANLE01315
Ursus americanus	123799561		URSAM29091

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Annotation

OrthoDB (Group)

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Acknowledgements