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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
angiotensin II receptor type 1
Summary
- Gene Symbol
-
- AGTR1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Disease variant
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Host-virus interaction
- Palmitate
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| D3DNG8 |
|
| P30556 |
|
| Q6NUP5 |
|
| A0A0A0MSE3 |
|
| Q53YY0 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of phospholipase A2 activity | ||
| positive regulation of protein metabolic process | ||
| calcium-mediated signaling | ||
| Rho protein signal transduction | ||
| regulation of renal sodium excretion |
GO Hierarchy
biological process
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| angiotensin type I receptor activity | ||
| protein heterodimerization activity | ||
| bradykinin receptor binding | ||
| angiotensin type II receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- type-1 angiotensin ii receptor
- Functional Category
-
- K: Transcription
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| phospholipase C-activating angiotensin-activated signaling pathway |
| positive regulation of cytosolic calcium ion concentration |
| regulation of vasoconstriction |
| InterPro |
|---|
| Angiotensin II receptor family |
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:5844 | myocardial infarction | |
| DOID:0050851 | glomerulosclerosis | |
| DOID:0060224 | atrial fibrillation | |
| DOID:0080600 | COVID-19 | |
| DOID:10652 | Alzheimer's disease | |
| DOID:1073 | renal hypertension | |
| DOID:10763 | hypertension | |
| DOID:10825 | essential hypertension | |
| DOID:10952 | nephritis | |
| DOID:11335 | sarcoidosis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 118291298 | SCOMX18187 | |||
| 118894942 | BALMU17708 | |||
| 122229703 | PANLE24525 | |||
| 123802390 | URSAM19857 | |||
| 129033939 | 9600_0:00103e |
