essential hypertension

Summary
Synonym
  • idiopathic hypertension
  • primary hypertension
Definition
A hypertension with no known cause. It is the most common type of hypertension.
Super Class
hypertension
Disease Ontology
DOID:10825
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
MGI genotype (from TogoID)
Related Genes
Displaying entries 1 - 10 of 15 in total
Gene ID Gene Symbol Description Source
118 ADD1 adducin 1
185 AGTR1 angiotensin II receptor type 1
481 ATP1B1 ATPase Na+/K+ transporting subunit beta 1
488 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
847 CAT catalase
1577 CYP3A5 cytochrome P450 family 3 subfamily A member 5
1889 ECE1 endothelin converting enzyme 1
3290 HSD11B1 hydroxysteroid 11-beta dehydrogenase 1
4846 NOS3 nitric oxide synthase 3
4882 NPR2 natriuretic peptide receptor 2
Displaying 1 entry
Gene ID Gene Symbol Description Source
18127 Nos3 nitric oxide synthase 3, endothelial cell
The Human Phenotype Ontology
Displaying all 4 entries
HPO ID HPO Term
HP:0004421 Elevated systolic blood pressure
HP:0005117 Elevated diastolic blood pressure
HP:0001426 Non-Mendelian inheritance
HP:0004972 Elevated mean arterial pressure
Displaying all 2 entries
Gene ID Gene Symbol Description
1577 CYP3A5 cytochrome P450 family 3 subfamily A member 5
5740 PTGIS prostaglandin I2 synthase

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025