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nitric oxide synthase 3

Summary

Gene Symbol

NOS3

Organism

Homo sapiens (human)

External Links

NCBI Gene

4846

PubChem

4846

Alliance of Genome Resources

HGNC:7876

Annotation

Keyword

3D-structure
Alternative splicing
Calcium
Calmodulin-binding
Cell membrane
Cytoskeleton
Direct protein sequencing
FAD
FMN
Golgi apparatus
Heme
Myristate
NADP
Oxidoreductase
Palmitate
Phosphoprotein
Proteomics identification
Reference proteome
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0S0A6	Constitutive NOS EC-NOS NOS type III Nitric oxide synthase, endothelial
P29474	Constitutive NOS EC-NOS NOS type III Nitric oxide synthase, endothelial

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 54 in total

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GO Term	Evidence Code	PMID
angiogenesis	IEA
ovulation from ovarian follicle	IEA
in utero embryonic development	IEA
blood vessel remodeling	ISS
regulation of sodium ion transport	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

nitric oxide biosynthetic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine catabolic process

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

pteridine-containing compound metabolic process [inference]

tetrahydrobiopterin metabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

reactive nitrogen species metabolic process [inference]

nitric oxide metabolic process

nitric oxide biosynthetic process

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

nitric oxide biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine catabolic process

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

cellular aromatic compound metabolic process [inference]

pteridine-containing compound metabolic process [inference]

tetrahydrobiopterin metabolic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

nitric oxide biosynthetic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

nitric oxide biosynthetic process

heterocycle metabolic process [inference]

pteridine-containing compound metabolic process [inference]

tetrahydrobiopterin metabolic process

reactive oxygen species metabolic process [inference]

superoxide metabolic process [inference]

removal of superoxide radicals

primary metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine catabolic process

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

diol metabolic process [inference]

tetrahydrobiopterin metabolic process

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine catabolic process

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine catabolic process

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

organic cyclic compound metabolic process [inference]

pteridine-containing compound metabolic process [inference]

tetrahydrobiopterin metabolic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine catabolic process

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

pteridine-containing compound metabolic process [inference]

tetrahydrobiopterin metabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

diol metabolic process [inference]

tetrahydrobiopterin metabolic process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

lipopolysaccharide-mediated signaling pathway

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

nitric oxide mediated signal transduction

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine catabolic process

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

cellular aromatic compound metabolic process [inference]

pteridine-containing compound metabolic process [inference]

tetrahydrobiopterin metabolic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

nitric oxide biosynthetic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

nitric oxide biosynthetic process

heterocycle metabolic process [inference]

pteridine-containing compound metabolic process [inference]

tetrahydrobiopterin metabolic process

reactive oxygen species metabolic process [inference]

superoxide metabolic process [inference]

removal of superoxide radicals

cell motility [inference]

cell migration [inference]

ameboidal-type cell migration [inference]

epithelial cell migration [inference]

endothelial cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization

cellular detoxification [inference]

cellular oxidant detoxification [inference]

removal of superoxide radicals

reproductive process [inference]

ovulation cycle process [inference]

ovulation from ovarian follicle

multicellular organismal reproductive process [inference]

ovulation [inference]

ovulation from ovarian follicle

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle adaptation [inference]

smooth muscle adaptation [inference]

smooth muscle hyperplasia

muscle hyperplasia [inference]

smooth muscle hyperplasia

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance

vasodilation

endocrine process [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of systemic arterial blood pressure by endothelin

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

tissue remodeling [inference]

blood vessel remodeling

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

homeostasis of number of cells within a tissue

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

homeostasis of number of cells within a tissue

developmental process [inference]

anatomical structure morphogenesis [inference]

heart valve morphogenesis [inference]

tissue morphogenesis [inference]

mesenchyme morphogenesis [inference]

endocardial cushion morphogenesis

cardiac septum morphogenesis [inference]

ventricular septum morphogenesis

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

animal organ development [inference]

lung development

homeostatic process [inference]

cellular homeostasis [inference]

cell redox homeostasis

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

homeostasis of number of cells within a tissue

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

homeostasis of number of cells within a tissue

rhythmic process [inference]

ovulation cycle process [inference]

ovulation from ovarian follicle

response to stimulus [inference]

response to stress [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to heat

response to endogenous stimulus [inference]

response to hormone

response to chemical [inference]

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to hormone

response to lipid [inference]

response to lipopolysaccharide

response to oxygen-containing compound [inference]

response to lipopolysaccharide

muscle adaptation [inference]

smooth muscle adaptation [inference]

smooth muscle hyperplasia

muscle hyperplasia [inference]

smooth muscle hyperplasia

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

organic substance transport [inference]

calcium ion transport

establishment of localization in cell

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of nucleotide biosynthetic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of small molecule metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide biosynthetic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of nucleotide biosynthetic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of phosphate metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide biosynthetic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide biosynthetic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of small molecule metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide biosynthetic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of small molecule metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide biosynthetic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway [inference]

positive regulation of Notch signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of extrinsic apoptotic signaling pathway [inference]

regulation of extrinsic apoptotic signaling pathway via death domain receptors [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of localization [inference]

regulation of transport [inference]

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of sodium ion transport

regulation of potassium ion transport [inference]

negative regulation of potassium ion transport

regulation of calcium ion transport [inference]

negative regulation of calcium ion transport

negative regulation of monoatomic ion transport [inference]

negative regulation of transport [inference]

negative regulation of monoatomic ion transport [inference]

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

regulation of blood vessel endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of small molecule metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of developmental process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of smooth muscle cell proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of cell activation [inference]

negative regulation of platelet activation

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of muscle adaptation [inference]

negative regulation of muscle hyperplasia

negative regulation of response to external stimulus [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation

negative regulation of response to wounding [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation

negative regulation of transport [inference]

negative regulation of monoatomic ion transport [inference]

negative regulation of developmental process [inference]

negative regulation of biomineral tissue development

negative regulation of multicellular organismal process [inference]

negative regulation of muscle adaptation [inference]

negative regulation of muscle hyperplasia

negative regulation of coagulation [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation

negative regulation of cell activation [inference]

negative regulation of platelet activation

negative regulation of hemostasis [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway [inference]

positive regulation of Notch signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of extrinsic apoptotic signaling pathway [inference]

regulation of extrinsic apoptotic signaling pathway via death domain receptors [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of response to external stimulus [inference]

regulation of blood coagulation [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation

negative regulation of response to external stimulus [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation

regulation of muscle adaptation [inference]

regulation of muscle hyperplasia [inference]

negative regulation of muscle hyperplasia

negative regulation of muscle adaptation [inference]

negative regulation of muscle hyperplasia

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of muscle adaptation [inference]

negative regulation of muscle hyperplasia

negative regulation of response to external stimulus [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation

negative regulation of response to wounding [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation

regulation of response to stress [inference]

regulation of response to wounding [inference]

regulation of wound healing [inference]

regulation of blood coagulation [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation

negative regulation of wound healing [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation

negative regulation of response to wounding [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

negative regulation of developmental process [inference]

negative regulation of biomineral tissue development

positive regulation of developmental process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

negative regulation of biomineral tissue development

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

lipopolysaccharide-mediated signaling pathway

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

nitric oxide mediated signal transduction

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway [inference]

positive regulation of Notch signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of extrinsic apoptotic signaling pathway [inference]

regulation of extrinsic apoptotic signaling pathway via death domain receptors [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide biosynthetic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of nucleotide biosynthetic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of phosphate metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide biosynthetic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

negative regulation of smooth muscle cell proliferation

regulation of smooth muscle cell proliferation [inference]

negative regulation of smooth muscle cell proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

regulation of extrinsic apoptotic signaling pathway [inference]

regulation of extrinsic apoptotic signaling pathway via death domain receptors [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of smooth muscle cell proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

negative regulation of cell activation [inference]

negative regulation of platelet activation

regulation of cell activation [inference]

regulation of platelet activation [inference]

negative regulation of platelet activation

negative regulation of cell activation [inference]

negative regulation of platelet activation

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

regulation of blood vessel endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

regulation of multicellular organismal process [inference]

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

regulation of blood vessel endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

regulation of system process [inference]

regulation of nervous system process

regulation of muscle system process [inference]

regulation of muscle adaptation [inference]

regulation of muscle hyperplasia [inference]

negative regulation of muscle hyperplasia

negative regulation of muscle adaptation [inference]

negative regulation of muscle hyperplasia

regulation of blood circulation [inference]

regulation of heart contraction [inference]

regulation of the force of heart contraction [inference]

regulation of the force of heart contraction by chemical signal

regulation of coagulation [inference]

regulation of blood coagulation [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation

negative regulation of coagulation [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation

regulation of cell activation [inference]

regulation of platelet activation [inference]

negative regulation of platelet activation

negative regulation of cell activation [inference]

negative regulation of platelet activation

positive regulation of multicellular organismal process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

negative regulation of multicellular organismal process [inference]

negative regulation of muscle adaptation [inference]

negative regulation of muscle hyperplasia

negative regulation of coagulation [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation

negative regulation of cell activation [inference]

negative regulation of platelet activation

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

negative regulation of biomineral tissue development

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of hemostasis [inference]

regulation of blood coagulation [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation

negative regulation of hemostasis [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation

regulation of biological quality [inference]

regulation of the force of heart contraction [inference]

regulation of the force of heart contraction by chemical signal

regulation of blood pressure

regulation of systemic arterial blood pressure [inference]

regulation of systemic arterial blood pressure mediated by a chemical signal [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of systemic arterial blood pressure by endothelin

negative regulation of blood pressure

regulation of body fluid levels [inference]

regulation of hemostasis [inference]

regulation of blood coagulation [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation

negative regulation of hemostasis [inference]

negative regulation of blood coagulation [inference]

negative regulation of platelet activation

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance

vasodilation

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of lyase activity [inference]

positive regulation of guanylate cyclase activity

regulation of catalytic activity [inference]

regulation of cyclase activity [inference]

positive regulation of cyclase activity [inference]

positive regulation of guanylate cyclase activity

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of catalytic activity [inference]

positive regulation of cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of lyase activity [inference]

positive regulation of guanylate cyclase activity

regulation of lyase activity [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of lyase activity [inference]

positive regulation of guanylate cyclase activity

detoxification [inference]

cellular detoxification [inference]

cellular oxidant detoxification [inference]

removal of superoxide radicals

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
Golgi membrane	TAS
nucleus	ISS
nucleus	IBA
cytoplasm	ISS
cytoplasm	IDA	9794441

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endocytic vesicle membrane

bounding membrane of organelle [inference]

plasma membrane region [inference]

plasma membrane raft [inference]

caveola

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft [inference]

caveola

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
actin monomer binding	IPI	17502619
nitric-oxide synthase activity	EXP	1378832
nitric-oxide synthase activity	TAS
nitric-oxide synthase activity	IDA	1378832 19666465 35772285 7488039
nitric-oxide synthase activity	IMP	23707606

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

monooxygenase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [inference]

nitric-oxide synthase activity

oxidoreductase activity, acting on NAD(P)H [inference]

oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor [inference]

superoxide-generating NAD(P)H oxidase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [inference]

nitric-oxide synthase activity

binding [inference]

protein binding

calmodulin binding

cytoskeletal protein binding [inference]

actin binding [inference]

actin monomer binding

scaffold protein binding

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

amino acid binding [inference]

arginine binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

ribonucleotide binding [inference]

FMN binding

flavin adenine dinucleotide binding

ion binding [inference]

anion binding [inference]

FMN binding

carboxylic acid binding [inference]

amino acid binding [inference]

arginine binding

flavin adenine dinucleotide binding

cation binding [inference]

arginine binding

metal ion binding [inference]

transition metal ion binding [inference]

cadmium ion binding

organic cyclic compound binding [inference]

tetrahydrobiopterin binding

tetrapyrrole binding [inference]

heme binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

ribonucleotide binding [inference]

FMN binding

flavin adenine dinucleotide binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

FMN binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Nitric oxide synthase

Functional Category

P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms
V: Defense mechanisms

Displaying **all 5** entries
Gene Ontology
calmodulin binding
metal ion binding
nitric oxide biosynthetic process
nitric-oxide synthase activity
oxidoreductase activity

Displaying **all 7** entries
InterPro
FAD-binding domain, ferredoxin reductase-type
Ferredoxin-NADP reductase (FNR), nucleotide-binding domain
Flavoprotein pyridine nucleotide cytochrome reductase
NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily
Oxidoreductase FAD/NAD(P)-binding
Riboflavin synthase-like beta-barrel
Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding

Disease

Disease Ontology

Displaying entries **1 - 10** of 36 in total

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DO ID	Disease Name	Source
DOID:0050700	cardiomyopathy	Alliance of Genome Resources
DOID:0050848	obstructive sleep apnea	Alliance of Genome Resources
DOID:0050852	limb ischemia	Alliance of Genome Resources
DOID:0060496	respiratory allergy	Alliance of Genome Resources
DOID:10159	osteonecrosis	Alliance of Genome Resources
DOID:10283	prostate cancer	Alliance of Genome Resources
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:1070	primary open angle glaucoma	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:10825	essential hypertension	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements