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11-beta-hydroxysteroid dehydrogenase 1

Summary

UniProt ID

P28845

Gene Symbol

HSD11B1
HSD11
HSD11L
SDR26C1

Organism

Homo sapiens (human)

External Links

GlyConnect

1158

GlyGen

P28845

PubChem

P28845

SwissLipids

SLP:000000809

The Human Metabolome Database

HMDBP00718

Annotation

Keyword

3D-structure
Disease variant
Endoplasmic reticulum
Glycoprotein
NADP
Oxidoreductase
Reference proteome
Signal-anchor
Steroid metabolism
Transmembrane helix

Gene Ontology (GO)

Displaying **all 2** entries
GO Term
steroid catabolic process
lung development

Displaying **all 3** entries
GO Term
endoplasmic reticulum membrane
membrane
intracellular membrane-bounded organelle

Displaying **all 6** entries
GO Term
protein homodimerization activity
7-beta-hydroxysteroid dehydrogenase (NADP+) activity
NADP binding
11-beta-hydroxysteroid dehydrogenase (NADP+) activity
cortisol dehydrogenase activity
steroid binding

Annotation information from UniProt.

Sequence

MAFMKKYLLPILGLFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPCRKILEFLYSTSYNMDRFINK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
123	N-linked (GlcNAc...) asparagine	19159218	G64527OM	UniProt GlyGen GlyConnect
162	N-linked (GlcNAc...) asparagine	19159218	G25451PN G80920RR G62765YT G31852PQ G41247ZX	UniProt GlyGen GlyConnect
207	N-linked (GlcNAc...) asparagine			UniProt GlyGen