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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
adducin 1
Summary
- Gene Symbol
-
- ADD1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Acetylation
- Actin-binding
- Alternative splicing
- Calmodulin-binding
- Cell membrane
- Cytoskeleton
- Direct protein sequencing
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A804HL01 |
|
| P35611 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| actin cytoskeleton organization | ||
| cellular response to calcium ion | ||
| positive regulation of protein binding | ||
| positive regulation of establishment of endothelial barrier | ||
| positive regulation of adherens junction organization |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of actin filament-based process [inference]
regulation of cell differentiation [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| focal adhesion | ||
| postsynaptic density | ||
| plasma membrane | ||
| adherens junction | ||
| nucleoplasm |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| actin binding | ||
| actin filament binding | ||
| spectrin binding | ||
| calmodulin binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- adducin
- Functional Category
-
- E: Amino acid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| actin filament binding |
| InterPro |
|---|
| Class II aldolase/adducin N-terminal domain superfamily |
| Class II aldolase/adducin N-terminal |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0081361 | spastic quadriplegic cerebral palsy 3 | |
| DOID:10591 | pre-eclampsia | |
| DOID:10763 | hypertension | |
| DOID:10825 | essential hypertension | |
| DOID:10908 | hydrocephalus | |
| DOID:11044 | gastroschisis | |
| DOID:13809 | familial combined hyperlipidemia | |
| DOID:1936 | atherosclerosis | |
| DOID:1969 | cerebral palsy | |
| DOID:2986 | IgA glomerulonephritis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 11518 | MGI:87918 | MOUSE44081 | ||
| 24170 | RGD:2041 | RATNO08180 | ||
| 37230 | FB:FBgn0263391 | |||
| 179647 | WB:WBGene00000073 | |||
| 394387 | Xenbase:XB-GENE-995035 | |||
| 398686 | Xenbase:XB-GENE-17340904 | |||
| 448173 | Xenbase:XB-GENE-995030 | |||
| 488796 | CANLF12171 | |||
| 507193 | BOVIN31943 | |||
| 555511 | ZFIN:ZDB-GENE-030909-2 | DANRE20506 |
