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Alpha-adducin

Summary

UniProt ID

P35611

Gene Symbol

ADD1
ADDA

Organism

Homo sapiens (human)

External Links

GlyGen: P35611
PubChem: P35611
The O-GlcNAc Database: P35611
RaftProt: P35611
O-GlcNAcAtlas: P35611

Annotation

Keyword

Acetylation
Actin-binding
Alternative splicing
Calmodulin-binding
Cell membrane
Cytoskeleton
Direct protein sequencing
Phosphoprotein
Reference proteome

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
barbed-end actin filament capping
positive regulation of establishment of endothelial barrier
positive regulation of adherens junction organization
actin cytoskeleton organization
positive regulation of protein binding
actin filament bundle assembly
cellular response to calcium ion

Displaying entries **1 - 10** of 11 in total

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GO Term
cytosol
nucleoplasm
adherens junction
focal adhesion
F-actin capping protein complex
postsynaptic density
nuclear body
nucleus
cytoplasm
cytoskeleton

Displaying **all 10** entries
GO Term
spectrin binding
protein homodimerization activity
protein heterodimerization activity
protein dimerization activity
actin binding
actin filament binding
calmodulin binding
RNA binding
cadherin binding
RNA polymerase II-specific DNA-binding transcription factor binding

Annotation information from UniProt.

Sequence

MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILRNHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPVGEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYSFASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKKSDS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	GlyTouCan ID	Source
521	G49108TO	GlyGen The O-GlcNAc Database
540	G49108TO	GlyGen The O-GlcNAc Database
542	G49108TO	GlyGen The O-GlcNAc Database
557	G49108TO	GlyGen The O-GlcNAc Database
558	G49108TO G70994MS	GlyGen The O-GlcNAc Database
559	G49108TO	GlyGen The O-GlcNAc Database
565	G49108TO	GlyGen The O-GlcNAc Database
568	G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Caspase-mediated cleavage of cytoskeletal proteins	Homo sapiens
Miscellaneous transport and binding events	Homo sapiens
XBP1(S) activates chaperone genes	Homo sapiens

Human Protein Atlas

ENSG00000087274

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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