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MIRAGE
Renin

Summary
UniProt ID
P00797
Gene Symbol
  • REN
Gene ID
5972
Organism
Homo sapiens (human)
GlyConnect
GlyGen
P00797
PubChem
P00797
The Human Metabolome Database
HMDBP02624
Re-Glyco
P00797
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Aspartyl protease
  • Cleavage on pair of basic residues
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • Glycoprotein
  • Membrane
  • Reference proteome
  • Secreted
  • Signal
  • Zymogen
Gene Ontology (GO)
Displaying all 4 entries
GO Term
extracellular region
extracellular space
plasma membrane
apical part of cell
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MDGWRRMPRWGLLLLLWGSCTFGLPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 4 entries
Position Description PubMed ID GlyTouCan ID Source
71 N-linked (GlcNAc...) asparagine
141 N-linked (GlcNAc...) asparagine
378
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
Metabolism of Angiotensinogen to Angiotensins Homo sapiens
Disease
Displaying all 5 entries
DO ID Disease Name Source
DOID:0060062 familial juvenile hyperuricemic nephropathy
DOID:10762 portal hypertension
DOID:10763 hypertension
DOID:10825 essential hypertension
DOID:10881 hand, foot and mouth disease
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025