GlyCosmos Portal

Displaying entries **6 - 10** of 11 in total

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GO Term	Evidence Code	PMID
cell-cell junction	IDA	23793062
phosphatidylinositol 3-kinase complex	IBA ISO TAS	9988280
membrane	IDA	16043515
perinuclear region of cytoplasm	IDA	11038173
protein-containing complex	ISO

GO Hierarchy

cellular component

protein-containing complex

membrane protein complex [inference]

phosphatidylinositol 3-kinase complex

phosphatidylinositol 3-kinase complex, class I [inference]

phosphatidylinositol 3-kinase complex, class IA

catalytic complex [inference]

transferase complex [inference]

transferase complex, transferring phosphorus-containing groups [inference]

phosphatidylinositol 3-kinase complex

phosphatidylinositol 3-kinase complex, class I [inference]

phosphatidylinositol 3-kinase complex, class IA

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

perinuclear endoplasmic reticulum membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

perinuclear region of cytoplasm

Displaying entries **1 - 5** of 25 in total

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GO Term	Evidence Code	PMID
kinase activator activity	IDA IMP ISO	11784871 7504175 7534300 7542745
ATPase binding	ISO
insulin-like growth factor receptor binding	ISO
phosphatidylinositol 3-kinase regulatory subunit binding	IPI	20348926
platelet-derived growth factor receptor binding	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

lipid kinase activity [inference]

phosphatidylinositol kinase activity [inference]

1-phosphatidylinositol-3-kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

phosphatidylinositol kinase activity [inference]

1-phosphatidylinositol-3-kinase activity

binding [inference]

protein binding

signaling receptor binding

cytokine receptor binding [inference]

neurotrophin receptor binding [inference]

neurotrophin TRK receptor binding [inference]

neurotrophin TRKA receptor binding

growth factor receptor binding [inference]

platelet-derived growth factor receptor binding

calmodulin binding

transcription factor binding [inference]

DNA-binding transcription factor binding [inference]

RNA polymerase II-specific DNA-binding transcription factor binding [inference]

nuclear receptor binding [inference]

nuclear estrogen receptor binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

protein tyrosine kinase binding [inference]

receptor tyrosine kinase binding

phosphatase binding [inference]

protein phosphatase binding

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

ATPase binding

protein domain specific binding

phosphatidylinositol 3-kinase binding [inference]

phosphatidylinositol 3-kinase regulatory subunit binding

protein dimerization activity [inference]

protein heterodimerization activity

phosphoprotein binding

protein phosphorylated amino acid binding [inference]

phosphotyrosine residue binding

amide binding [inference]

peptide binding [inference]

peptide hormone binding [inference]

insulin binding

hormone binding [inference]

peptide hormone binding [inference]

insulin binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

kinase activator activity

kinase regulator activity [inference]

molecular function activator activity [inference]

enzyme activator activity [inference]

kinase activator activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying entries **11 - 20** of 21 in total

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DO ID	Disease Name	Source
DOID:2871	endometrial carcinoma	Alliance of Genome Resources
DOID:3910	lung adenocarcinoma	Alliance of Genome Resources
DOID:4450	renal cell carcinoma	Alliance of Genome Resources
DOID:5409	lung small cell carcinoma	Alliance of Genome Resources
DOID:684	hepatocellular carcinoma	Alliance of Genome Resources
DOID:7148	rheumatoid arthritis	Alliance of Genome Resources
DOID:7305	astroblastoma	Alliance of Genome Resources
DOID:8398	osteoarthritis	Alliance of Genome Resources
DOID:9256	colorectal cancer	Alliance of Genome Resources
DOID:9352	type 2 diabetes mellitus	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 90 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	172141	WB:WBGene00000001
Drosophila melanogaster	33203	FB:FBgn0020622
Callorhinchus milii	103177781		CALMI13836
Latimeria chalumnae	102353218		LATCH10685
Danio rerio	557176	ZFIN:ZDB-GENE-030131-1280	DANRE35848
Astyanax mexicanus	103046618		ASTMX18374
Ictalurus punctatus	108260231		ICTPU23291
Electrophorus electricus	113588232		ELEEL41173
Salmo salar	106563018		SALSA17670
Salmo salar	106567700		SALSA70895

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