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Phosphatidylinositol 3-kinase regulatory subunit alpha

Summary

UniProt ID

P26450

Gene Symbol

Pik3r1

Organism

Mus musculus (house mouse)

External Links

GlyGen: P26450
PubChem: P26450
O-GlcNAcAtlas: P26450

Annotation

Keyword

Acetylation
Direct protein sequencing
Phosphoprotein
Protein transport
Reference proteome
Repeat
SH2 domain
SH3 domain
Stress response
Ubl conjugation

Gene Ontology (GO)

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GO Term
intracellular glucose homeostasis
positive regulation of protein phosphorylation
positive regulation of leukocyte migration
glucose metabolic process
negative regulation of cell adhesion
insulin receptor signaling pathway
positive regulation of gene expression
B cell differentiation
osteoclast differentiation
positive regulation of cell migration

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GO Term
nucleus
cytoplasm
cell-cell junction
membrane
protein-containing complex
perinuclear endoplasmic reticulum membrane
cytosol
cis-Golgi network
phosphatidylinositol 3-kinase complex
phosphatidylinositol 3-kinase complex, class IA

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GO Term
signaling receptor binding
insulin binding
kinase activator activity
protein kinase binding
ATPase binding
protein domain specific binding
nuclear estrogen receptor binding
ubiquitin protein ligase binding
ErbB-3 class receptor binding
insulin receptor substrate binding

Annotation information from UniProt.

Sequence

MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEDIGWLNGYNETTGERGDFPGTYVEYIGRKRISPPTPKPRPPRPLPVAPGSSKTEADTEQQALPLPDLAEQFAPPDVAPPLLIKLLEAIEKKGLECSTLYRTQSSSNPAELRQLLDCDAASVDLEMIDVHVLADAFKRYLADLPNPVIPVAVYNEMMSLAQELQSPEDCIQLLKKLIRLPNIPHQCWLTLQYLLKHFFKLSQASSKNLLNARVLSEIFSPVLFRFPAASSDNTEHLIKAIEILISTEWNERQPAPALPPKPPKPTTVANNSMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNHDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
541			G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	Mus musculus
CD28 dependent PI3K/Akt signaling	Mus musculus
CDC42 GTPase cycle	Mus musculus
Costimulation by the CD28 family	Mus musculus
DAP12 signaling	Mus musculus
Downstream TCR signaling	Mus musculus
Downstream signal transduction	Mus musculus
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	Mus musculus
Extra-nuclear estrogen signaling	Mus musculus
FLT3 Signaling	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements