FLT3 Signaling

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
FLT3LG dimerFLT3LG dimer:FLT3FLT3FLT3LG dimer:FLT3 dimerATPADPActive FLT3Grap2active FLT3:GRAP2active FLT3:GRB10Grb10active FLT3:p-Y GRB10Pik3r1active FLT3:p-Y GRB10:PIK3R1Pik3caactive FLT3:p-Y GRB10:PI3KActive FLT3: GRB2Active FLT3:GRB2:SOS1Sos1p21 RAS:GDPp21 RAS:GTPGDPGTPActive FLT3:GRB2:p-Y GAB2:PI3KActive FLT3:GRB2:p-Y-GAB2:PIK3R1ATPQ9WVH4Foxo3ADPQ9WVH4P46414Cdkn1b
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025