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MIRAGE
GTPase KRas
Summary
- UniProt ID
- P32883
- Gene Symbol
-
- Kras
- Kras2
- Gene ID
- 16653
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Alternative splicing
- Cell membrane
- Cytoplasm
- GTP-binding
- Hydrolase
- Isopeptide bond
- Methylation
- Palmitate
- Prenylation
- Proto-oncogene
- Reference proteome
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| plasma membrane |
| endomembrane system |
| membrane |
| cytoplasmic side of plasma membrane |
| GO Term |
|---|
| GTPase activity |
| protein-membrane adaptor activity |
| protein-containing complex binding |
| G protein activity |
| GTP binding |
Sequence
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQELARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCVIM
Glycosylation Sites
G13037JM
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of RAS in B cells | Mus musculus |
| CD209 (DC-SIGN) signaling | Mus musculus |
| Ca2+ pathway | Mus musculus |
| DAP12 signaling | Mus musculus |
| Downstream signal transduction | Mus musculus |
| EGFR Transactivation by Gastrin | Mus musculus |
| Estrogen-stimulated signaling through PRKCZ | Mus musculus |
| FCERI mediated MAPK activation | Mus musculus |
| FLT3 Signaling | Mus musculus |
| FRS-mediated FGFR1 signaling | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050458 | juvenile myelomonocytic leukemia | |
| DOID:0060581 | Noonan syndrome 3 | |
| DOID:0060688 | arteriovenous malformations of the brain | |
| DOID:10283 | prostate cancer | |
| DOID:1324 | lung cancer | |
| DOID:289 | endometriosis | |
| DOID:4905 | pancreatic carcinoma | |
| DOID:4928 | intrahepatic cholangiocarcinoma |
