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MIRAGE
FCERI mediated MAPK activation

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
ATPADPMAPK8,9,10p-MAPK8,9,10p-MAPK8,9,10JunADPP05627ATPFosP01101p-2S-cJUN:p-2S,2T-cFOSO54957p-5Y-LAT:p-SHC1:GRB2:SOS1p-SHC1:GRB2:SOSp-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:SLP76GADS:SLP76p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:SLP76:PLCGPLC gamma1,2p21 RAS:GDPp21 RAS:GTPGDPGTPShc1P98083GRB2-1:SOS1p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCGp-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAVVAV1,2,3p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAVRAC1:GDPp-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTPPAK dimerp-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimerp-2Y-PAKMAP2K4P47809MAP2K7Q8CE90
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
a simple tooltip
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025