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Tyrosine-protein kinase Lyn

Summary

UniProt ID

P25911

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

GlyGen: P25911
PubChem: P25911
The Human Metabolome Database: HMDBP13813
The O-GlcNAc Database: P25911
RaftProt: P25911
O-GlcNAcAtlas: P25911

Annotation

Keyword

3D-structure
ATP-binding
Adaptive immunity
Alternative splicing
Cell membrane
Cytoplasm
Golgi apparatus
Inflammatory response
Innate immunity
Myristate
Nucleus
Palmitate
Phosphoprotein
Proto-oncogene
Reference proteome
SH2 domain
SH3 domain
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

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GO Term
response to amino acid
B cell homeostasis
regulation of cytokine production
negative regulation of protein phosphorylation
hematopoietic progenitor cell differentiation
adaptive immune response
histamine secretion by mast cell
platelet degranulation
negative regulation of myeloid leukocyte differentiation
regulation of B cell apoptotic process

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GO Term
nucleus
cytoplasm
Golgi apparatus
plasma membrane
glutamatergic synapse
mitochondrial crista
cytosol
mitochondrial membrane
membrane raft
adherens junction

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GO Term
protein kinase activity
protein tyrosine kinase activity
signaling receptor binding
SH3 domain binding
ubiquitin protein ligase binding
gamma-tubulin binding
ephrin receptor binding
phosphoprotein binding
transmembrane transporter binding
non-membrane spanning protein tyrosine kinase activity

Annotation information from UniProt.

Sequence

MGCIKSKRKDNLNDDEVDSKTQPVRNTDRTIYVRDPTSNKQQRPVPEFHLLPGQRFQTKDPEEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLSSKREGFIPSNYVAKVNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDYDPMHGDVIKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQSDGLCRRLEKACISPKPQKPWDKDAWEIPRESIKLVKKLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLYAVVTKEEPIYIITEFMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMSALSQGYRMPRMENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTATEGQYQQQP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
19			G49108TO	GlyGen The O-GlcNAc Database
267			G29068FM	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
CD209 (DC-SIGN) signaling	Mus musculus
CD22 mediated BCR regulation	Mus musculus
CD28 co-stimulation	Mus musculus
CTLA4 inhibitory signaling	Mus musculus
Cell surface interactions at the vascular wall	Mus musculus
Cyclin D associated events in G1	Mus musculus
Dectin-2 family	Mus musculus
EPH-ephrin mediated repulsion of cells	Mus musculus
EPHA-mediated growth cone collapse	Mus musculus
EPHB-mediated forward signaling	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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External Links

Annotation

International Collaboration

Acknowledgements