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MIRAGE
EPHB-mediated forward signaling

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTPp-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2PIP2p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actinG-actinARP2/3 complex (ATP bound)p-EPHB:EFNB oligomersEFNBs:p-EPHBs:KALRNKALRNGTPRAC1:GTPRAC1:GDPGDPPAK1 dimerRAC1:GTP:PAK1 dimer:RAC1:GTPATPRAC1-GTP:p-S144,T423-PAK1ADPP97433EFNBs:p-EPHBs:p-Y397-PTK2:ARHGEF28EFNBs:p-EPHBs:p-Y397-PTK2RHOA:GDPRhoA:GTPGDPRHOA:GTP:ROCK1,ROCK2ROCK1,ROCK2Tiam1EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly:TIAM1EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:GlyEFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly:p-Y829-TIAM1Rac1-GTPRAC1:GDPp-EPHBs:EFNBs:RASA1p-EPHBs:EFNBs:RASA1:HRAS:GTPHRAS:GTPH2OPip-EPHBs:EFNBs:RASA1:HRAS:GDPSdc2P43407p-Y179,Y191-SDC2 cluster
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.2.1

Last updated: April 7, 2025