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Dual specificity mitogen-activated protein kinase kinase 4

Summary

UniProt ID

P47809

Gene Symbol

Jnkk1
Map2k4
Mek4
Mkk4
Prkmk4
Sek1
Serk1
Skk1

Gene ID

26398

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003634
GlyGen: P47809
PubChem: P47809
Re-Glyco: P47809

Annotation

Keyword

ATP-binding
Acetylation
Apoptosis
Cytoplasm
Methylation
Nucleus
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
Stress response
Tyrosine-protein kinase

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
nucleus
axon
dendrite cytoplasm
cytosol
perikaryon

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 12 in total

1

2

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GO Term
cell growth involved in cardiac muscle cell development
cellular response to mechanical stimulus
intrinsic apoptotic signaling pathway in response to hydrogen peroxide
positive regulation of DNA replication
positive regulation of JNK cascade
positive regulation of nitric-oxide synthase biosynthetic process
response to wounding
positive regulation of neuron apoptotic process
smooth muscle cell apoptotic process
cellular response to sorbitol

Displaying **all 6** entries
GO Term
protein serine kinase activity
histone H2AXY142 kinase activity
JUN kinase kinase activity
histone H3Y41 kinase activity
protein serine/threonine kinase activity
ATP binding

Annotation information from UniProt.

Sequence

MAAPSPSGGGGSGGGGGTPGPIGPPASGHPAVSSMQGKRKALKLNFANPPVKSTARFTLNPNTTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERTVEVACYVCKILDQMPATPSSPMYVD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	GlyTouCan ID	Source
18		GlyGen
62	G80920RR	GlycoProtDB GlyGen
389		GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
FCERI mediated MAPK activation	Mus musculus
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	Mus musculus
Oxidative Stress Induced Senescence	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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International Collaboration

Acknowledgements