Extra-nuclear estrogen signaling

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
H+TPNO2L-ArgNOTPNHH2OL-CitPalmS-ESRsMe-PalmS-ESRsSAHAdoMetESRsESRs:HSBP1 oligomerHSBP1 oligomerPALM-CoACoA-SHPalmS-ESRsPalmS-ESRs:CAVsCAVsCAVsESTG:Me-PalmS-ESR dimersESTGStrnPalmS-ESRs:STRN:ESTGHeterotrimeric G-protein Gi (inactive)ESTG:ESRs:STRN:heterotrimeric G(i) proteinESRs:STRN:ESTGG-protein alpha (i):GDPG-protein beta-gamma complexESRs:STRN:ESTG:MyrG-SRCP05480ATPESRs:STRN:ESTG:MyrG-pY419-SRCADPESRs:STRN:ESTG:MyrG-pY419 SRC:PI3K alphaPI3K alphaP34152Me260-ESR1:STRN:ESTG: MyrG-pY419 SRC:PI3Kalpha:pY-PTK2Me260-ESR1:STRN:ESTG:MyrG-pY419 SRC:PI3K alphaESTG:Me260-ESR1 dimerESTG:ESR1:p-3Y-IGF1R:SHC1Shc1p-Y1161,1165,1166-IGF1RHbegfHbegfHbegfEGF-like ligands:p-6Y EGFR dimerEGF-like ligands:p-6Y EGFR:PTK2PTK2EGF-like ligands:p-6Y EGFR dimer:p-Y397 PTK2SPGS1PS1P:S1PR3S1pr3
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025