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Estrogen receptor

Summary

UniProt ID

P19785

Gene Symbol

Esr
Esr1
Estr
Estra
Nr3a1

Gene ID

13982

Organism

Mus musculus (house mouse)

External Links

GlyConnect

Estrogen receptor

GlyGen

P19785

PubChem

P19785

The O-GlcNAc Database

P19785

O-GlcNAcAtlas

P19785

Re-Glyco

P19785

Annotation

Keyword

Activator
Cell membrane
Cytoplasm
DNA-binding
Glycoprotein
Golgi apparatus
Methylation
Nucleus
Palmitate
Phosphoprotein
Receptor
Reference proteome
Steroid-binding
Transcription regulation
Ubl conjugation
Zinc-finger

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
euchromatin
nucleus
cytoplasm
plasma membrane
Golgi apparatus
transcription regulator complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 40 in total

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GO Term
negative regulation of gene expression
negative regulation of mitotic nuclear division
epithelial cell development
transcription by RNA polymerase II
phospholipase C-activating G protein-coupled receptor signaling pathway
androgen metabolic process
intracellular steroid hormone receptor signaling pathway
negative regulation of smooth muscle cell apoptotic process
negative regulation of DNA-binding transcription factor activity
fibroblast proliferation

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GO Term
chromatin binding
zinc ion binding
transcription corepressor binding
DNA-binding transcription activator activity, RNA polymerase II-specific
steroid binding
protein kinase binding
nuclear estrogen receptor binding
identical protein binding
sequence-specific DNA binding
ATPase binding

Annotation information from UniProt.

Sequence

MTMTLHTKASGMALLHQIQGNELEPLNRPQLKMPMERALGEVYVDNSKPTVFNYPEGAAYEFNAAAAAAAAASAPVYGQSGIAYGPGSEAAAFSANSLGAFPQLNSVSPSPLMLLHPPPQLSPFLHPHGQQVPYYLENEPSAYAVRDTGPPAFYRSNSDNRRQNGRERLSSSNEKGNMIMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDLEGRNEMGASGDMRAANLWPSPLVIKHTKKNSPALSLTADQMVSALLDAEPPMIYSEYDPSRPFSEASMMGLLTNLADRELVHMINWAKRVPGFGDLNLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHRRLAQLLLILSHIRHMSNKGMEHLYNMKCKNVVPLYDLLLEMLDAHRLHAPASRMGVPPEEPSQTQLATTSSTSAHSLQTYYIPPEAEGFPNTI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
10	O-linked (GlcNAc) serine	11226831	G49108TO	UniProt GlyGen The O-GlcNAc Database
50	O-linked (GlcNAc) threonine	11226831	G49108TO	UniProt GlyGen The O-GlcNAc Database
575	O-linked (GlcNAc) threonine	11226831 8999954	G49108TO	UniProt GlyGen The O-GlcNAc Database GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 12 in total

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Pathway Name	Organism
ESR-mediated signaling	Mus musculus
Estrogen-dependent gene expression	Mus musculus
Extra-nuclear estrogen signaling	Mus musculus
Mitochondrial unfolded protein response (UPRmt)	Mus musculus
Nuclear Receptor transcription pathway	Mus musculus
Nuclear signaling by ERBB4	Mus musculus
Ovarian tumor domain proteases	Mus musculus
PI3K/AKT Signaling	Mus musculus
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Mus musculus
RUNX1 regulates estrogen receptor mediated transcription	Mus musculus

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1612	breast cancer	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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External Links

Annotation

International Collaboration

Acknowledgements