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protein tyrosine phosphatase receptor type B

Summary

Gene Symbol

Ptprb

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

19263

PubChem

19263

Alliance of Genome Resources

MGI:97809

Annotation

Keyword

Angiogenesis
Glycoprotein
Phosphoprotein
Protein phosphatase
Proteomics identification
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A1W2P7W3
B2RU80	Vascular endothelial protein tyrosine phosphatase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
glial cell migration	ISO
angiogenesis	IBA IDA IMP	16514057 17360632 19451274
peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity	IDA	26063811
dephosphorylation	IDA ISO	10557082 12234928

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

macromolecule modification [inference]

protein modification process [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

cell motility [inference]

cell migration [inference]

glial cell migration

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	IEA
receptor complex	IBA ISO	23382219

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

cellular anatomical entity [inference]

membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cadherin binding	IBA ISO
protein tyrosine phosphatase activity	IEA
protein binding	IPI	10557082 12234928

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

binding [inference]

protein binding

cell adhesion molecule binding [inference]

cadherin binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying entries **1 - 10** of 12 in total

1

2

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DO ID	Disease Name	Source
DOID:0001816	angiosarcoma	Alliance of Genome Resources
DOID:0060108	brain glioma	Alliance of Genome Resources
DOID:0080199	colorectal carcinoma	Alliance of Genome Resources
DOID:1115	sarcoma	Alliance of Genome Resources
DOID:3068	glioblastoma	Alliance of Genome Resources
DOID:3347	osteosarcoma	Alliance of Genome Resources
DOID:3498	pancreatic ductal adenocarcinoma	Alliance of Genome Resources
DOID:3908	lung non-small cell carcinoma	Alliance of Genome Resources
DOID:3910	lung adenocarcinoma	Alliance of Genome Resources
DOID:3963	thyroid gland carcinoma	Alliance of Genome Resources