osteosarcoma

Summary
Synonym
  • Osteogenic sarcoma
  • Skeletal sarcoma
  • bone tissue neoplasm
  • osteoid sarcoma
Definition
A bone sarcoma that is located_in bone that has_material_basis_in cells of mesenchymal origin. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus).
Super Class
bone sarcoma
Disease Ontology
DOID:3347
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying all 10 entries
Gene ID Gene Symbol Description Source
780 DDR1 discoidin domain receptor tyrosine kinase 1
988 CDC5L cell division cycle 5 like
1869 E2F1 E2F transcription factor 1
2146 EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
5176 SERPINF1 serpin family F member 1
5925 RB1 RB transcriptional corepressor 1
7157 TP53 tumor protein p53
7852 CXCR4 C-X-C motif chemokine receptor 4
11200 CHEK2 checkpoint kinase 2
30008 EFEMP2 EGF containing fibulin extracellular matrix protein 2
Displaying 1 entry
Gene ID Gene Symbol Description Source
22059 Trp53 transformation related protein 53
Displaying 1 entry
Gene ID Gene Symbol Description Source
24842 Tp53 tumor protein p53
Displaying 1 entry
Gene ID Gene Symbol Description Source
852092 PHO8 alkaline phosphatase PHO8

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Acknowledgements

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Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025