Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / OrganismsTools
SugarDrawer
GlycanBuilder
Glycan Converters
GlycoMaple
GlycomeAtlas
LM-GlycomeAtlas
GALAXY
MCAW
GlycoSim
GRable
Guidelines
MIRAGE
Histone-lysine N-methyltransferase EZH2
Summary
- UniProt ID
- Q15910
- Gene Symbol
-
- EZH2
- KMT6
- Gene ID
- 2146
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Biological rhythms
- Chromatin regulator
- Disease variant
- Glycoprotein
- Isopeptide bond
- Methyltransferase
- Nucleus
- Phosphoprotein
- Reference proteome
- Repressor
- S-adenosyl-L-methionine
- Transcription regulation
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| pronucleus |
| nucleoplasm |
| chromosome, telomeric region |
| chromatin silencing complex |
| pericentric heterochromatin |
| ESC/E(Z) complex |
| chromatin |
| nucleus |
| chromosome |
| synapse |
Sequence
MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFPDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRRGRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 73 |
|
|||
| 75 | O-linked (GlcNAc) serine | |||
| 76 |
|
|||
| 84 |
|
|||
| 87 |
|
|||
| 313 |
|
|||
| 729 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | Homo sapiens |
| Defective pyroptosis | Homo sapiens |
| HCMV Early Events | Homo sapiens |
| Oxidative Stress Induced Senescence | Homo sapiens |
| PKMTs methylate histone lysines | Homo sapiens |
| PRC2 methylates histones and DNA | Homo sapiens |
| Regulation of PTEN gene transcription | Homo sapiens |
| Transcriptional Regulation by E2F6 | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050861 | colorectal adenocarcinoma | |
| DOID:0050866 | oral squamous cell carcinoma | |
| DOID:0050908 | myelodysplastic syndrome | |
| DOID:0080188 | chronic myelomonocytic leukemia | |
| DOID:10534 | stomach cancer | |
| DOID:1324 | lung cancer | |
| DOID:14731 | Weaver syndrome | |
| DOID:3068 | glioblastoma | |
| DOID:3347 | osteosarcoma | |
| DOID:4947 | cholangiocarcinoma |
