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MIRAGE
C-X-C chemokine receptor type 4
Summary
- UniProt ID
- P61073
- Gene Symbol
-
- CXCR4
- Gene ID
- 7852
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P61073
- PubChem
- P61073
- The Human Metabolome Database
- HMDBP07643
- Re-Glyco
- P61073
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell junction
- Cell membrane
- Disease variant
- Disulfide bond
- Endosome
- G-protein coupled receptor
- Host cell receptor for virus entry
- Host-virus interaction
- Isopeptide bond
- Lysosome
- Phosphoprotein
- Proteoglycan
- Reference proteome
- Sulfation
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| lysosome |
| plasma membrane |
| cytoplasmic vesicle |
| protein-containing complex |
| anchoring junction |
| early endosome |
| late endosome |
| external side of plasma membrane |
| cell surface |
Sequence
MEGISIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFANVSEADDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Binding and entry of HIV virion | Homo sapiens |
| Chemokine receptors bind chemokines | Homo sapiens |
| Formation of definitive endoderm | Homo sapiens |
| G alpha (i) signalling events | Homo sapiens |
| Signaling by ROBO receptors | Homo sapiens |
| Specification of primordial germ cells | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060591 | WHIM syndrome 1 | |
| DOID:0060901 | lymphoplasmacytic lymphoma | |
| DOID:10283 | prostate cancer | |
| DOID:10534 | stomach cancer | |
| DOID:11476 | osteoporosis | |
| DOID:3347 | osteosarcoma | |
| DOID:4074 | pancreatic adenocarcinoma | |
| DOID:5603 | T-cell acute lymphoblastic leukemia | |
| DOID:615 | leukopenia | |
| DOID:9119 | acute myeloid leukemia |
