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ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4

Summary

Gene Symbol

St6galnac4

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

20448

KEGG Gene ID

mmu:20448

PubChem

20448

Alliance of Genome Resources

MGI:1341894

Annotation

Keyword

Alternative splicing
Disulfide bond
Glycosyltransferase
Golgi apparatus
Lipid metabolism
Proteomics identification
Reference proteome
Sialic acid
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9R2B6	NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase ST6GalNAc IV Sialyltransferase 7D
Q8C3J2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein glycosylation	IEA
oligosaccharide metabolic process	IBA
ganglioside biosynthetic process	IBA
lipid metabolic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

amide metabolic process [inference]

ceramide metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

amide biosynthetic process [inference]

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

glycosphingolipid metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

glycosphingolipid metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

lipid metabolic process

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

glycosphingolipid metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

lipid metabolic process

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

glycosphingolipid metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

glycosphingolipid metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

glycosphingolipid metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process [inference]

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
Golgi membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity	IBA
alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

sialyltransferase activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1, 3-N-acetyl-galactosaminide alpha-2,

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism

Displaying **all 5** entries
Gene Ontology
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity
ganglioside biosynthetic process
lipid metabolic process
sialyltransferase activity
transferase activity

Displaying **all 2** entries
InterPro
GT29-like superfamiliy
Glycosyl transferase family 29

KEGG BRITE Database

Orthology

K03374

Name

N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7D) [EC:2.4.3.7]

References

10207017

Reactions

Displaying **all 2** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05914	2.4.3.3 2.4.3.7	G65562ZE	G01614ZM
R05959	2.4.3.7	G03277YI	G45714BQ

Rhea

an α-Neu5Ac-(2→3)-β-D-Gal-(1→3)-D-GlcNAc derivative + CMP-N-acetyl-β-neuraminate

an α-Neu5Ac-(2→3)-β-D-Gal-(1→3)-[α-Neu5Ac-(2→6)]-D-GlcNAc-R + H⁺ + CMP

Enzyme

2.4.3.7

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP000775
Gene Name: ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4

Ortholog

Displaying entries **51 - 60** of **103** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Propithecus coquereli	105806599			PROCO11362
Microcebus murinus	105875232			MICMU09022
Dipodomys ordii	105989432	10020_0:0024ff
Equus asinus asinus	106845456			EQUAS15673
Marmota marmota marmota	107152058	9994_0:0027bd
Sinocyclocheilus grahami	107585701			SINGR36471
Ictalurus punctatus	108279162			ICTPU11024
Crocodylus porosus	109313875			CROPO20043
Castor canadensis	109686789	51338_0:0019ce
Phascolarctos cinereus	110193695			PHACI24703

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Last updated: December 9, 2024