G01614ZM

Summary
GlyTouCan ID
G01614ZM
IUPAC Condensed
Neu5Ac(a2-3)Gal(b1-3)[Neu5Ac(a2-6)]GalNAc(a1-
Motifs
Di-sialyl T antigen
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
965.33
GlyConnect structure
GlyGen
ChEBI
PubChem Compound
PubChem Substance
Organisms
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying all 5 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
ST6GALNAC4 CMP-Neu5Ac
G65562ZE
R
G01614ZM
R
ST6GALNAC1 CMP-Neu5Ac
G65562ZE
Ser/Thr
G01614ZM
Ser/Thr
ST6GALNAC3 CMP-Neu5Ac
G65562ZE
Ser/Thr
G01614ZM
Ser/Thr
ST6GALNAC2 CMP-Neu5Ac
G65562ZE
Ser/Thr
G01614ZM
Ser/Thr
ST6GALNAC4 CMP-Neu5Ac
G65562ZE
Ser/Thr
G01614ZM
Ser/Thr
Displaying entries 1 - 5 of 6 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
ST6GALNAC4 CMP-Neu5Ac
G65562ZE
R
G01614ZM
R
ST6GALNAC1 CMP-Neu5Ac
G65562ZE
Ser/Thr
G01614ZM
Ser/Thr
ST6GALNAC3 CMP-Neu5Ac
G65562ZE
Ser/Thr
G01614ZM
Ser/Thr
ST6GALNAC2 CMP-Neu5Ac
G65562ZE
Ser/Thr
G01614ZM
Ser/Thr
ST6GALNAC4 CMP-Neu5Ac
G65562ZE
Ser/Thr
G01614ZM
Ser/Thr
KEGG BRITE Database
KEGG ID
Enzyme
References
Reactions
Displaying 1 entry
KEGG Reaction Enzyme Acceptor Product
R05914
GlycoEpitope
Epitope ID
EP0023
GlycomeAtlas

Tissues in which this glycan is expressed are highlighted in yellow.

Danio rerio
Brain Gill Heart Intestine Intestine Liver Ovary Skin Testis
Literature
Tissue
  • brain
  • gill
  • heart
  • intestine
  • liver
  • skin gland
  • testis
Reference
Yamakawa N et al. Systems glycomics of adult zebrafish identifies organ-specific sialylation and glycosylation patterns. Nat Commun. 2018;9(1):4647. Published 2018 Nov 7. doi:10.1038/s41467-018-06950-3
DOI
10.1038/s41467-018-06950-3
Sequence Descriptors
GlycoCT
RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
3b:b-dgal-HEX-1:5
4b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
5s:n-acetyl
6b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
7s:n-acetyl
LIN
1:1d(2+1)2n
2:1o(3+1)3d
3:3o(3+2)4d
4:4d(5+1)5n
5:1o(6+2)6d
6:6d(5+1)7n
WURCS
WURCS=2.0/3,4,3/[a2112h-1a_1-5_2*NCC/3=O][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O]/1-2-3-3/a3-b1_a6-d2_b3-c2
PubAnnotation
Displaying all 4 entries
Title Authors Source Publication Date PubMed ID
Reduction in disialyl-T antigen levels in mice deficient for both St6galnac3 and St6galnac4 results in blood filling of lymph nodes.
  • Fuseya S
  • Izumi H
  • Hamano A
  • Murakami Y
  • Suzuki R
  • Koiwai R
  • Hayashi T
  • Kuno A
  • Takahashi S
  • Kudo T
Sci Rep 2023 Jun 29 37386100
Mammalian sialyltransferases allow efficient Escherichia coli-based production of mucin-type O-glycoproteins but can also transfer Kdo.
  • Sim L
  • Thompson N
  • Geissner A
  • Withers SG
  • Wakarchuk WW
Glycobiology 2022 Apr 21 34939113
Majority of alpha2,6-sialylated glycans in the adult mouse brain exist in O-glycans: SALSA-MS analysis for knockout mice of alpha2,6-sialyltransferase genes.
  • Ohmi Y
  • Nishikaze T
  • Kitaura Y
  • Ito T
  • Yamamoto S
  • Sugiyama F
  • Matsuyama M
  • Takahashi Y
  • Takeda A
  • Kawahara T
  • Okajima T
  • Furukawa K
  • Furukawa K
Glycobiology 2021 Jun 3 33242079
Potent glycan inhibitors of myelin-associated glycoprotein enhance axon outgrowth in vitro.
  • Vyas AA
  • Blixt O
  • Paulson JC
  • Schnaar RL
J Biol Chem 2005 Apr 22 15701648

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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