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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
coagulation factor IX
Summary
- Gene Symbol
-
- F9
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calcium
- Cleavage on pair of basic residues
- Direct protein sequencing
- Disease variant
- Disulfide bond
- EGF-like domain
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hemophilia
- Hydroxylation
- Magnesium
- Metal-binding
- Pharmaceutical
- Phosphoprotein
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Sulfation
- Thrombophilia
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| P00740 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| zymogen activation | ||
| blood coagulation |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi lumen | ||
| collagen-containing extracellular matrix | ||
| endoplasmic reticulum lumen | ||
| plasma membrane | ||
| extracellular region |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| metal ion binding | ||
| endopeptidase activity | ||
| calcium ion binding | ||
| serine-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- coagulation factor IX
- Functional Category
-
- E: Amino acid transport and metabolism
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| blood coagulation |
| calcium ion binding |
| hydrolase activity |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
| zymogen activation |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080839 | X-linked warfarin sensitivity | |
| DOID:0111899 | X-linked thrombophilia due to factor IX defect | |
| DOID:12259 | hemophilia B | |
| DOID:9352 | type 2 diabetes mellitus |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 14071 | MGI:88384 | MOUSE65901 | ||
| 24946 | RGD:2589 | RATNO45583 | ||
| 359826 | ZFIN:ZDB-GENE-030714-2 | |||
| 397518 | PIGXX38123 | |||
| 404015 | CANLF20209 | |||
| 443316 | SHEEP20071 | |||
| 445943 | TAKRU12538 | |||
| 465887 | 9598_0:00585f | PANTR46921 | ||
| 493973 | FELCA39228 | |||
| 496659 | Xenbase:XB-GENE-941626 |
