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neuromedin U receptor 2

Summary

Gene Symbol

Nmur2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

216749

PubChem

216749

Alliance of Genome Resources

MGI:2441765

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8BZ39

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 8** of 8 in total

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GO Term	Evidence Code	PMID
grooming behavior	IMP	17030627
reduction of food intake in response to dietary excess	IMP	17030627
phospholipase C-activating G protein-coupled receptor signaling pathway	IEA ISO

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

multicellular organismal process [inference]

behavior [inference]

grooming behavior

feeding behavior [inference]

eating behavior [inference]

reduction of food intake in response to dietary excess

multicellular organismal response to stress [inference]

response to pain

response to stimulus [inference]

response to stress [inference]

multicellular organismal response to stress [inference]

response to pain

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

secretion [inference]

icosanoid secretion [inference]

arachidonic acid secretion

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

organic substance transport [inference]

lipid transport [inference]

fatty acid transport [inference]

long-chain fatty acid transport [inference]

arachidonate transport [inference]

arachidonic acid secretion

organic anion transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

fatty acid transport [inference]

long-chain fatty acid transport [inference]

arachidonate transport [inference]

arachidonic acid secretion

icosanoid transport [inference]

icosanoid secretion [inference]

arachidonic acid secretion

arachidonate transport [inference]

arachidonic acid secretion

organic acid transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

fatty acid transport [inference]

long-chain fatty acid transport [inference]

arachidonate transport [inference]

arachidonic acid secretion

icosanoid transport [inference]

icosanoid secretion [inference]

arachidonic acid secretion

arachidonate transport [inference]

arachidonic acid secretion

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of nervous system process [inference]

regulation of sensory perception [inference]

regulation of sensory perception of pain

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	IC ISO	15635449
plasma membrane	IBA IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
neuromedin U receptor activity	IEA ISO
neuropeptide receptor activity	IBA IPI ISO	15635449
intracellular calcium activated chloride channel activity	IEA ISO
neuromedin U binding	IEA ISO
GTP binding	IEA ISO

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity [inference]

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

monoatomic anion transmembrane transporter activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity [inference]

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

chloride transmembrane transporter activity [inference]

chloride channel activity [inference]

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic anion transmembrane transporter activity [inference]

chloride transmembrane transporter activity [inference]

chloride channel activity [inference]

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity [inference]

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

salt transmembrane transporter activity [inference]

chloride transmembrane transporter activity [inference]

chloride channel activity [inference]

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

binding [inference]

amide binding [inference]

peptide binding [inference]

neuropeptide binding [inference]

neuromedin U binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

neuropeptide receptor activity

neuromedin U receptor activity

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

neuropeptide receptor activity

neuromedin U receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Neuromedin U receptor

Functional Category

E: Amino acid transport and metabolism
K: Transcription
L: Replication, recombination and repair
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 3** entries
Gene Ontology
neuromedin U receptor activity
neuropeptide receptor activity
neuropeptide signaling pathway

Displaying **all 5** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM
Neuromedin U receptor, type 2
Neuromedin U receptor
Neuromedin-U receptor 2, C-terminal domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:9970	obesity	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of **108** in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	566750	ZFIN:ZDB-GENE-130530-567
Danio rerio	569960	ZFIN:ZDB-GENE-131121-154
Macaca mulatta	714051		MACMU38765
Equus caballus	100071477		HORSE07856
Ornithorhynchus anatinus	100077498		ORNAN28803
Sus scrofa	100217382		PIGXX10949
Taeniopygia guttata	100222313		TAEGU04269
Oryctolagus cuniculus	100345574		RABIT09505
Callithrix jacchus	100388765		CALJA26981
Pongo abelii	100447920		PONAB29765