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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
transforming growth factor, beta receptor I
Summary
- Gene Symbol
-
- Tgfbr1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Alternative splicing
- Apoptosis
- Cell membrane
- Differentiation
- Disulfide bond
- Glycoprotein
- Growth regulation
- Isopeptide bond
- Magnesium
- Manganese
- Metal-binding
- Phosphoprotein
- Proteomics identification
- Receptor
- Reference proteome
- Serine/threonine-protein kinase
- Signal
- Tight junction
- Transmembrane helix
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| anterior/posterior pattern specification | ||
| positive regulation of cell population proliferation | ||
| blastocyst development | ||
| endothelial cell proliferation | ||
| positive regulation of stress fiber assembly |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of response to stimulus [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of cell population proliferation [inference]
regulation of programmed cell death [inference]
regulation of cellular component biogenesis [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| activin receptor complex | ||
| transforming growth factor beta ligand-receptor complex | ||
| protein-containing complex | ||
| apical plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| type II transforming growth factor beta receptor binding | ||
| protein binding | ||
| SMAD binding | ||
| signaling receptor binding | ||
| protein-containing complex binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- TGF-beta receptor type-1
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
- X: Mobilome: prophages, transposons
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050466 | Loeys-Dietz syndrome | |
| DOID:0070235 | Loeys-Dietz syndrome 1 | |
| DOID:11054 | urinary bladder cancer | |
| DOID:127 | leiomyoma | |
| DOID:2256 | osteochondrodysplasia | |
| DOID:3498 | pancreatic ductal adenocarcinoma | |
| DOID:3883 | Lynch syndrome | |
| DOID:418 | systemic scleroderma | |
| DOID:557 | kidney disease | |
| DOID:5585 | Ferguson-Smith tumor |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 7046 | HGNC:11772 | HUMAN97796 | ||
| 29591 | 10116_1:0021c1 | RGD:3852 | RATNO34357 | |
| 35900 | FB:FBgn0011300 | |||
| 174044 | WB:WBGene00004860 | |||
| 176829 | WB:WBGene00000897 | |||
| 282382 | BOVIN34648 | |||
| 396665 | PIGXX15794 | |||
| 445775 | CIOIN15800 | |||
| 472992 | PANTR44450 | |||
| 548715 | Xenbase:XB-GENE-478587 |
