systemic scleroderma

Summary
Synonym
  • Scleroderma
  • Scleroderma syndrome
  • progressive systemic sclerosis
  • systemic sclerosis
Definition
A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.
Super Class
scleroderma
Disease Ontology
DOID:418
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 1 - 10 of 66 in total
Gene ID Gene Symbol Description Source
177 AGER advanced glycosylation end-product specific receptor
183 AGT angiotensinogen
308 ANXA5 annexin A5
627 BDNF brain derived neurotrophic factor
629 CFB complement factor B
718 C3 complement C3
942 CD86 CD86 molecule
1116 CHI3L1 chitinase 3 like 1
1191 CLU clusterin
1235 CCR6 C-C motif chemokine receptor 6
Displaying entries 1 - 10 of 57 in total
Gene ID Gene Symbol Description Source
11421 Ace angiotensin I converting enzyme
11596 Ager advanced glycosylation end product-specific receptor
11747 Anxa5 annexin A5
12064 Bdnf brain derived neurotrophic factor
12266 C3 complement component 3
12458 Ccr6 C-C motif chemokine receptor 6
12524 Cd86 CD86 antigen
12654 Chi3l1 chitinase 3 like 1
12759 Clu clusterin
12766 Cxcr3 C-X-C motif chemokine receptor 3
Displaying entries 1 - 10 of 36 in total
Gene ID Gene Symbol Description Source
24179 Agt angiotensinogen
24225 Bdnf brain-derived neurotrophic factor
24232 C3 complement C3
24310 Ace angiotensin I converting enzyme
24446 Hgf hepatocyte growth factor
24484 Igfbp3 insulin-like growth factor binding protein 3
24617 Serpine1 serpin family E member 1
24770 Ccl2 C-C motif chemokine ligand 2
24854 Clu clusterin
24890 Esr1 estrogen receptor 1
Displaying all 10 entries
Gene ID Gene Symbol Description Source
31926 Idgf4 Imaginal disc growth factor 4
34091 Spn28Dc Serpin 28Dc
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
34978 Idgf1 Imaginal disc growth factor 1
34979 Idgf2 Imaginal disc growth factor 2
34981 Idgf3 Imaginal disc growth factor 3
36868 Idgf6 Imaginal disc growth factor 6
37104 Idgf5 Imaginal disc growth factor 5
42490 Mvl Malvolio
Displaying all 5 entries
Gene ID Gene Symbol Description Source
30682 vegfaa vascular endothelial growth factor Aa
58133 ngfb nerve growth factor b (beta polypeptide)
554230 kdr kinase insert domain receptor (a type III receptor tyrosine kinase)
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
791973 cxcr3.2 chemokine (C-X-C motif) receptor 3, tandem duplicate 2
Displaying all 2 entries
Gene ID Gene Symbol Description Source Organism
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
108709389 ngf.S nerve growth factor S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source
174044 sma-6 Serine/threonine-protein kinase receptor sma-6
175182 ver-1 Protein ver-1
176076 fbn-1 EGF-like domain-containing protein
176282 lin-12 lin-12/Notch intracellular domain
176286 glp-1 glp-1/Notch intracellular domain
176829 daf-1 Cell surface receptor daf-1
177044 smf-3 NRAMP-like transporter smf-3
178672 srp-3 Serpin domain-containing protein
178748 zmp-3 Matrix metalloproteinase-C
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
Displaying all 2 entries
Gene ID Gene Symbol Description Source
850721 SMF3 putative divalent metal ion transporter SMF3
851977 CTS2 putative chitinase

About Release Notes Help Feedback

Click here to visit the beta site.


International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International


GlyCosmos Portal v4.1.0

Last updated: December 9, 2024