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MIRAGE
Stromelysin-1
Summary
- UniProt ID
- P08254
- Gene Symbol
-
- MMP3
- STMY1
- Gene ID
- 4314
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P08254
- PubChem
- P08254
- The Human Metabolome Database
- HMDBP02592
- Re-Glyco
- P08254
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Collagen degradation
- Cytoplasm
- Direct protein sequencing
- Disulfide bond
- Extracellular matrix
- Innate immunity
- Metal-binding
- Metalloprotease
- Nucleus
- Reference proteome
- Repeat
- Signal
- Zinc
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| extracellular space |
| nucleus |
| mitochondrion |
| extracellular matrix |
| cytosol |
| GO Term |
|---|
| serine-type endopeptidase activity |
| zinc ion binding |
| endopeptidase activity |
| metalloendopeptidase activity |
| peptidase activity |
| metallopeptidase activity |
Sequence
MKSLPILLLLCVAVCSAYPLDGAARGEDTSMNLVQKYLENYYDLKKDVKQFVRRKDSGPVVKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPPDSPETPLVPTEPVPPEPGTPANCDPALSFDAVSTLRGEILIFKDRHFWRKSLRKLEPELHLISSFWPSLPSGVDAAYEVTSKDLVFIFKGNQFWAIRGNEVRAGYPRGIHTLGFPPTVRKIDAAISDKEKNKTYFFVEDKYWRFDEKRNSMEPGFPKQIAEDFPGIDSKIDAVFEEFGFFYFFTGSSQLEFDPNAKKVTHTLKSNSWLNC
Glycosylation Sites
G43417UB
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of Matrix Metalloproteinases | Homo sapiens |
| Assembly of collagen fibrils and other multimeric structures | Homo sapiens |
| Collagen degradation | Homo sapiens |
| Degradation of the extracellular matrix | Homo sapiens |
| EGFR Transactivation by Gastrin | Homo sapiens |
| Extra-nuclear estrogen signaling | Homo sapiens |
| Interleukin-4 and Interleukin-13 signaling | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060224 | atrial fibrillation | |
| DOID:0060903 | thrombosis | |
| DOID:13001 | carotid stenosis | |
| DOID:14175 | von Hippel-Lindau disease | |
| DOID:1612 | breast cancer | |
| DOID:2349 | arteriosclerosis | |
| DOID:3393 | coronary artery disease | |
| DOID:418 | systemic scleroderma | |
| DOID:4450 | renal cell carcinoma | |
| DOID:4914 | esophagus adenocarcinoma |
