Collagen degradation

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Collagen type II fibrilCleaved collagen type II fibrilCollagen type VII fibrilCleaved collagen type VII fibrilCollagen type XIVCleaved collagen type XIVH2O2AMASNH35PHLPiCollagen type I fibrilCleaved collagen type I fibrilCollagen type III fibrilCleaved collagen type III fibrilCollagen IVCleaved collagen type IV networksCollagen VCleaved collagen type V fibrilCollagen type VI fibrilCleaved collagen type VI fibrilCollagen type VIII fibrilCleaved collagen type VIII fibrilCollagen type IXCleaved collagen type IXCollagen type X fibrilCleaved collagen type X fibrilCollagen type XI fibrilCleaved collagen type XI fibrilCollagen type XIICleaved collagen type XIICollagen type XV multimerCleaved collagen type XV multimerEndostatin-XVCollagen type XVICleaved tropocollagen type XVICollagen type XVIII multimerEndostatinCleaved collagen type XVIII multimerCollagen type XIIICleaved collagen type XIIICollagen alpha-1(XIII) ectodomainsCollagen type XVIICleaved collagen type XVIICollagen alpha-1(XVII) ectodomainsCollagen type XXIIICollagen alpha-1(XXIII) ectodomainsCleaved collagen type XXIIICollagen type XXVCleaved collagen type XXVCollagen alpha-1(XXV) ectodomainsCollagen type XIXCleaved collagen fibrils
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 1 - 10 of 35 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
O14672 Disintegrin and metalloproteinase domain-containing protein 10
  • ADAM10
  • KUZ
  • MADM
view
O60882 Matrix metalloproteinase-20
  • MMP20
view
P03956 Interstitial collagenase
  • CLG
  • MMP1
view
P07339 Cathepsin D
  • CPSD
  • CTSD
view
P07478 Trypsin-2
  • PRSS2
  • TRY2
  • TRYP2
view
P07711 Procathepsin L
  • CTSL
  • CTSL1
view
P07858 Cathepsin B
  • CPSB
  • CTSB
view
P08246 Neutrophil elastase
  • ELA2
  • ELANE
view
P08253 72 kDa type IV collagenase
  • CLG4A
  • MMP2
view
P08254 Stromelysin-1
  • MMP3
  • STMY1
view
Displaying 1 entry
GlyCosmos Lectin UniProt ID Lectin Name Pathway Viewer
GL_001410 P20849 Collagen alpha-1(IX) chain view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025