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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
fructose-bisphosphatase 1
Summary
- Gene Symbol
-
- FBP1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Allosteric enzyme
- Carbohydrate metabolism
- Direct protein sequencing
- Disease variant
- Gluconeogenesis
- Hydrolase
- Magnesium
- Metal-binding
- Nucleotide-binding
- Phosphoprotein
- Reference proteome
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cellular response to phorbol 13-acetate 12-myristate | ||
| fructose metabolic process | ||
| cellular hypotonic salinity response | ||
| sucrose biosynthetic process | ||
| cellular response to cAMP |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
response to stress [inference]
response to abiotic stimulus [inference]
response to chemical [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
negative regulation of cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| RNA polymerase II-specific DNA-binding transcription factor binding | ||
| AMP binding | ||
| monosaccharide binding | ||
| metal ion binding | ||
| protein binding |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3068 | glioblastoma | |
| DOID:3070 | high grade glioma | |
| DOID:3071 | gliosarcoma | |
| DOID:3074 | giant cell glioblastoma | |
| DOID:3347 | osteosarcoma | |
| DOID:3361 | childhood osteosarcoma | |
| DOID:3376 | bone osteosarcoma | |
| DOID:3459 | breast carcinoma | |
| DOID:3498 | pancreatic ductal adenocarcinoma | |
| DOID:3571 | liver cancer |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0002104 | Apnea |
| HP:0002119 | Ventriculomegaly |
| HP:0002149 | Hyperuricemia |
| HP:0002240 | Hepatomegaly |
| HP:0002329 | Drowsiness |
| HP:0002876 | Episodic tachypnea |
| HP:0002883 | Hyperventilation |
| HP:0002910 | Elevated circulating hepatic transaminase concentration |
| HP:0003128 | Lactic acidosis |
| HP:0003162 | Fasting hypoglycemia |
| Disease ID | Disease Name |
|---|---|
| ORPHA:348 |
|
| OMIM:229700 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100732473 | CAVPO15716 | ||
| 101573019 | OCTDE22351 | ||
| 101708632 | HETGA00873 | ||
| 100013279 | MONDO28643 | ||
| 102447388 | PELSI10704 | ||
| 103682232 | URSMA27637 | ||
| 113897421 | BOBOX31172 | ||
| 100963037 | OTOGA17804 | ||
| 101069203 | TAKRU44961 | ||
| 102004174 | CHILA07178 |
