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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
C-X-C motif chemokine receptor 1
Summary
- Gene Symbol
-
- Cxcr1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Cell membrane
- Chemotaxis
- Direct protein sequencing
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q810W6 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| chemotaxis | ||
| receptor internalization | ||
| calcium-mediated signaling | ||
| cell surface receptor signaling pathway | ||
| neutrophil chemotaxis |
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| interleukin-8 receptor activity | ||
| interleukin-8 binding | ||
| C-X-C chemokine receptor activity | ||
| C-C chemokine receptor activity | ||
| C-C chemokine binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- C-X-C chemokine receptor type 1
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- P: Inorganic ion transport and metabolism
| InterPro |
|---|
| CXC chemokine receptor 1/2 |
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080784 | urinary tract infection | |
| DOID:11400 | pyelonephritis | |
| DOID:2920 | membranoproliferative glomerulonephritis | |
| DOID:526 | human immunodeficiency virus infectious disease | |
| DOID:783 | end stage renal disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 3577 | HGNC:6026 | |||
| 54258 | 10116_1:00319c | RGD:2905 | RATNO43963 | |
| 188226 | WB:WBGene00011578 | |||
| 796724 | ZFIN:ZDB-GENE-100414-1 | DANRE43923 | ||
| 100012266 | MONDO31516 | |||
| 100012302 | MONDO31524 | |||
| 100083635 | ORNAN11453 | |||
| 100379619 | 10141_0:00062f | CAVPO23870 | ||
| 100554402 | ANOCA00677 | |||
| 100554601 | ANOCA00678 |
