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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
lysine demethylase 1A
Summary
- Gene Symbol
-
- KDM1A
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Chromatin regulator
- Chromosome
- Coiled coil
- Developmental protein
- Direct protein sequencing
- Disease variant
- FAD
- Isopeptide bond
- Nucleus
- Oxidoreductase
- Phosphoprotein
- Reference proteome
- Repressor
- Transcription regulation
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| O60341 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of neural precursor cell proliferation | ||
| guanine metabolic process | ||
| regulation of DNA methylation-dependent heterochromatin formation | ||
| DNA repair-dependent chromatin remodeling | ||
| positive regulation of neuron projection development |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of protein metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
negative regulation of signal transduction [inference]
regulation of intracellular signal transduction [inference]
regulation of apoptotic signaling pathway [inference]
negative regulation of signaling [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
negative regulation of metabolic process [inference]
negative regulation of signaling [inference]
negative regulation of cellular process [inference]
negative regulation of response to stimulus [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
negative regulation of signal transduction [inference]
regulation of intracellular signal transduction [inference]
regulation of apoptotic signaling pathway [inference]
negative regulation of response to stimulus [inference]
regulation of response to stress [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
negative regulation of signal transduction [inference]
regulation of intracellular signal transduction [inference]
regulation of apoptotic signaling pathway [inference]
negative regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of programmed cell death [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein-containing complex | ||
| chromosome, telomeric region | ||
| nucleoplasm | ||
| transcription regulator complex | ||
| chromatin |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Lysine-specific histone demethylase
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- P: Inorganic ion transport and metabolism
| Gene Ontology |
|---|
| chromatin binding |
| flavin adenine dinucleotide binding |
| oxidoreductase activity |
| InterPro |
|---|
| Amine oxidase |
| FAD/NAD(P)-binding domain superfamily |
| Homeobox-like domain superfamily |
| SWIRM domain |
| Winged helix-like DNA-binding domain superfamily |
Disease
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 40217 | FB:FBgn0260397 | |||
| 99982 | MGI:1196256 | MOUSE41158 | ||
| 173214 | WB:WBGene00005010 | |||
| 456614 | 9598_0:0006a7 | PANTR20216 | ||
| 500569 | RGD:1562975 | RATNO32858 | ||
| 532997 | BOVIN25221 | |||
| 558450 | ZFIN:ZDB-GENE-030131-7828 | |||
| 718609 | MACMU21230 | |||
| 100025161 | MONDO24416 | |||
| 100127157 | PIGXX29264 |
